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Articles on Depression

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Electroconvulsive therapy involves inducing a controlled seizure under anesthesia. Inkoly/iStock via Getty Images Plus

How electroconvulsive therapy heals the brain − new insights into ECT, a stigmatized yet highly effective treatment for depression

Electroconvulsive therapy often evokes inaccurate images of seizing bodies and smoking ears. Better understanding of how it reduces depression symptoms can illuminate new ways to treat mental illness.
Lifestyle changes may be our best hope of delaying dementia or not developing dementia at all. (Shutterstock)

Lifestyle changes can reduce dementia risk by maintaining brain plasticity — but the time to act is now

Lifestyle-related dementia risks are complex, with factors like sleep, exercise, diet and social contact interacting with things like cognitive reserve, neuroplasticity and inflammation in the body.
Ketamine is an anesthetic that must be administered carefully and by a health care professional. Jeniffer Fontan/iStock via Getty Images Plus

Ketamine can rapidly reduce symptoms of PTSD and depression, new study finds

The analysis shows that ketamine may start relieving symptoms of PTSD within one day, but it is still unclear how long the effects last and how many injections are needed to maintain benefits.
A transgender woman at a safe house supporting LGBTQ residents in Kampala, Uganda. Anti-gay laws make certain homosexual relationships punishable by death. Luke Dray/Getty Images

Young people with sexual or gender diversity are at higher risk of stopping their HIV treatment because of stigma and harsh laws

Stigmatised people living with HIV often suffer from fear, depression and abuse. It’s sometimes easier to stop a treatment regime than risk being ostracised or assaulted by the community.
Deep brain stimulation can alleviate treatment-resistant depression for some patients. PM Images/Digital Vision via Getty Images

Depression recovery can be hard to measure − new research on deep brain stimulation shows how objective biomarkers could help make treatment more precise

Deep brain stimulation can help some people with treatment-resistant depression feel better, but it can be unclear whether a bout of low mood is a relapse or a bad day.
While zuranolone represents an exciting advance in the treatment of postpartum depression, many questions about its potential impact remain unanswered. (Shutterstock)

Zuranolone for postpartum depression: Hope, hype or both?

Amid the fanfare about a new medication for postpartum depression, it’s important to remember that PPD is underdiagnosed and undertreated, and that safe and effective treatments already exist.

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