Articles on Clinical trials

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This African woman suffers from an autoimmune disease called vitiligo which causes the loss of skin pigment. By andreonegin/shutterstock.com

New treatment in the works for disfiguring skin disease, vitiligo

An autoimmune disease called vitiligo causes white spots to appear on the body, in some cases completely erasing an individual's pigmentation. But a new therapy is on the horizon.
Eczema, which is common in babies, is itchy and painful. silentalex88/Shutterstock.com

Applying live bacteria to skin improves eczema

In this clinical trial, the first of its kind, physicians explore whether directly applying a 'good' strain of bacteria to the skin can heal eczema
There are currently no effective treatments for Alzheimer’s disease, which causes may elders to live their last years without recognizing their loved ones, and unable to care for themselves. (Shutterstock)

Can the healthy brain offer clues to curing Alzheimer’s?

Study of the "memory centres" of the brain in adults offers hope for detecting Alzheimer's disease earlier -- before the onset of memory loss.
Health Canada is proposing a new system to fast-track urgent drugs for children, the elderly and those with serious or life-threatening conditions. This would rely on decisions made by regulators in other jurisdictions. (Shutterstock)

Should Health Canada rely on foreign assessment of new drugs?

Health Canada is proposing to allow some prescription drugs into the country with only 'cursory clinical review.' Here's why we should be worried.
The experimental technique of ‘deep brain stimulation’ has improved the lives of patients with treatment-resistant depression, despite the ‘failure’ of a large clinical trial. (Shutterstock)

Could an experimental brain surgery make you happier?

For some patients, drilling a hole in the skull and inserting an electrode into the 'sadness centre' of the brain offers relief from debilitating and otherwise treatment-resistant depression.
Even if they are not treated, only about three per cent of men will die of prostate cancer over their lifetime, most in their 70s or 80s. (Shutterstock)

Movember shavedown: Why you should not get your prostate checked

A family physician and public health researcher explains why he isn't getting a prostate cancer test in Movember or at any time in the near future.
A drug needs to pass quite a few hurdles before it gets to the market. The Conversation/Wes Mountain

Explainer: how do drugs get from the point of discovery to the pharmacy shelf?

Only around 10% of new drugs in development make it onto the market. A drug needs to go through animal trials, and then four phases of human trials to be deemed suitable for use in patients.
Randomisation is the only commonly accepted method of ensuring an unbiased estimate of the treatment effect. The Conversation/Wes Mountain

Randomised control trials: what makes them the gold standard in medical research?

A randomised controlled trial is the best way to compare a new treatment with the standard treatment. And randomising trial participants is a core feature of the experiment.

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