Professor Samir Brahmachar: ‘Why should drug discovery be kept in the Wright brothers’ era of trial and error?’
Professor Samir Brahmachari's innovative Open Source Drug Development allows thousands of researchers to work together to discover novel therapies for under-studied diseases.
The advent of genetic technologies has been reducing the time and cost attached to diagnosing rare genetic diseases.
Precision editing DNA allows for some amazing applications.
Researchers are starting to harness the potential of this much-hyped gene editing technique – with coming applications in medicine, biology and agriculture.
Our cells have a built-in genetic clock, tracking time… but how accurately?
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How do scientists figure out when evolutionary events – like species splitting away from a common ancestor – happened? It turns out our DNA is a kind of molecular clock, keeping time via genetic changes.
What could genomic medicine do in the future?
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Although genomics research has the potential to revolutionize medicine, it has limitations. It may not do much to prevent many of the leading causes of death.
Do we contain the most elaborate set of instructions?
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The answer – fewer than are in a banana – has implications for the study of human health and raises questions about what generates complexity anyway.
People get suspicious when ethically fraught science is discussed behind closed doors.
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A recent closed meeting about building synthetic genomes raised suspicions about just what scientists were planning, away from the public eye.
Genomes don’t translate easily into an understanding of disease.
Big data is all well and good, but if we want medical breakthroughs, we'll need big theory too.
How has a retrovirus survived intact within the human genome for millennia, and how has it affected us?
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As we consider the ethics of human gene editing, we need to understand what can and can't be meaningfully edited.
Gene editing allows us to eliminate any misspellings, introduce beneficial natural variants, or perhaps cut out or insert new genes.
Should the gathering of experts from around the world that's considering the scientific, ethical, and governance issues linked to research into gene editing ring alarm bells?
How 'junk' DNA threw a spanner in the works.
The 1000 Genome Project is comparing the genomes of thousands of people from around the world.
The 1000 Genome Project has revealed the genetic variations that exist among people around the world, and discovered that some people are missing many genes.
While many of the fruits of the human genome project could be decades away, DNA sequencing of drug-resistant bacteria has been striding forwards
Genome sequencing has the potential to improve the diagnosis of conditions caused by changes in the DNA.
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Rapid technological advances mean it’s faster and cheaper than ever to read a person’s entire genetic code, known as the genome. Genomic sequencing has two potential applications in health: the care of…
Before the technology can used more widely, we need to ensure its use will bring improvements in health, quality and duration of life.
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Sydney’s Garvan Institute is this week promoting its acquisition of an Illumina machine which it says can sequence the whole human genome for $1,000. The institute hopes genomic sequencing will become…
Scientists are one step closer to unravelling the genetic mystery of debilitating arthritis after research found 13 more…