At higher-than-prescribed doses, pregabalin causes sedation and euphoria.
Bruno van der Kraan
Ambulance call-outs associated with the misuse of pregabalin (Lyrica) have increased tenfold in Victoria since 2012, mirroring an increase in prescription rates.
The biological pathways related to physical and emotional pain overlap.
People who use painkillers for non-medical reasons often justify it as a form of self-medication for legitimate medical diagnoses such as depression, anxiety and stress.
Some people feel more pain than others.
Mikhail_Kayl / Shutterstock.com
Researchers are exploring the genetic differences that dictate why some people suffer greater pain than others, and how to translate these findings into personalized pain treatments.
Even the slightest touch of a D. moroides leaf can cause excruciating pain. An intense stinging, burning pain is felt immediately, then intensifies, reaching a peak after 20 – 30 minutes.
Marina Hurley, Author provided
Depending on the species, touching a stinging tree can be like 30 wasp stings at once or being burnt with hot acid and electrocuted at the same time.
Many people may misunderstand the basics about opioids. That prevents researchers from understanding the full scope of the epidemic.
Knee arthroscopy requires admission to hospital and an anaesthetic. It carries some risk of harm such as infection or further damage in the joint.
Doctors tend to overestimate how good their treatments are and underestimate the harms that come from them. But many studies have shown knee arthroscopy to no more effective than fake surgery.
Happy cake Happy cafe/Shutterstock.com
In one sense, the brain feels no pain. In another sense, it feels all the pain.
A boy with a paper cut.
Ouch! Who hasn't felt the effects of a paper cut and then cursed the gods or themselves for the injury? But have you ever wondered why they hurt so much? A professor of family medicine explains why.
Studies examining pain are hard to judge, since they’re based on participants’ self-reported pain levels.
There's some evidence osteopathy can reduce the need for pain medications.
The way opioids work on the brain makes finding non-opioid treatments for addiction very challenging.
AP Photo/Ted S. Warren
Two neuroscientists explain the cruel chemistry of opioid addiction and why this crisis could last a lifetime.
The U.S. has the highest daily opioid use rate in the world.
Most countries need to find a happy balance between the American attitude that all pain needs to be cured – and the ethos in other countries that pain is to be endured.
Scientists have taken atomic resolution snapshots of an opioid receptor interacting with a drug. Now they are using these images to design "biased" opioids that block pain without the dangerous side effects.
As doctors have learned more about the types of pain, they can better tailor treatment.
As knowledge of pain and the highly addictive nature of opioids has grown, so has the knowledge grown about pain and its origins. A pain specialist explains the intricacies, and how treatment is changing as a result.
Pain of the sick: ‘Anatomy of Expression,’ by Sir Charles Bell, 1806.
In today's opioid crisis, why are some people with addictions treated with empathy and others with disdain? The answer to that question has roots in the 19th century.
This won’t hurt a bit.
Does your child hate their visits to the pediatrician? Do they psyche themselves into a panic that the shot will hurt? The best strategy to calm an anxious child may be to reframe their expectations.
Every patient is different.
Each person experiences pain differently, depending on his or her genetic makeup. That makes it difficult to figure out what treatments patients need.
Middle-aged and elderly people taking up exercise shouldn't be put off by joint pain. It will pass.
Pain lets us know when there is something wrong, but sometimes our brains can trick us.
Mai Lam/The Conversation NY-BD-CC
Trust Me I’m An Expert: The science of pain.
The Conversation 58.7 MB (download)
Our podcast Trust Me, I'm An Expert, goes beyond the headlines and asks researchers to explain the evidence on issues making news. Today, we're talking pain and what science says about managing it.
When a pain signal gets to the brain, it lets your brain know there’s a big problem so we can respond.
AAP Image/DAN PELED
In short, pain medicine is able to block the processes that cause the feeling of pain. To understand why, you need to know a bit about how pain works.
A South Koren athlete receives acupuncture treatment.
As the Olympics head to the Far East this month, two radically different approaches to training and treating athletes will be on display.