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Articles sur Cancer drugs

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Depending on how you look at it, drugs that can act on multiple targets could be a boon instead of a challenge. Andrew Brookes/Image Source via Getty Images

Many medications affect more than one target in the body – some drug designers are embracing the ‘side effects’ that had been seen as a drawback

Many approved drugs work on the body in ways that researchers still aren’t entirely clear about. Seeing this as an opportunity instead of a flaw may lead to better treatments for complex conditions.
Cancer groundshot highlights that investment in improving access to treatments already proven to work saves more lives than discovery of a new treatment. (Shutterstock)

Cancer groundshot: Access to proven treatments must parallel development of new therapies

Globally, most cancer patients die not because they don’t have access to newer drugs, but because they don’t have access to even basic treatments. Cancer groundshot aims to improve treatment access.
SARS-CoV-2 turns on a cellular switch to build the tubes in this photo – called filopodia – that might help viral particles – the little spheres – spread more easily. Dr Elizabeth Fischer, NIAID NIH / Bouhaddou et al. Elsevier 2020

Coronavirus and cancer hijack the same parts in human cells to spread – and our team identified existing cancer drugs that could fight COVID-19

Kinases are cellular control switches. When they malfunction, they can cause cancer. The coronavirus hijacks these kinases to replicate, and cancer drugs that target them could fight COVID-19.
The effectiveness of a drug may be evaluated based on its potential to shrink tumours – but this doesn’t necessarily equate to improved survival rates. From shutterstock.com

Do new cancer drugs work? Too often we don’t really know (and neither does your doctor)

National drug regulators use evidence from clinical trials to decide whether new cancer drugs will be approved for use. But these studies are often flawed.
Having cancer is bad enough, and dealing with the costs and confusion of billing systems makes things harder. KieferPix/Shutterstock.com

Confusing and high bills for cancer patients add to anxiety and suffering

A cancer diagnosis is one of the scariest of all. The pain and fear are worsened by a confusing landscape of bills, opaque billing systems and changing insurance rules, rates and reimbursements.
Applications to list drugs on the PBS are usually submitted by the manufacturers of those drugs. from shutterstock.com

We don’t need to change how we subsidise ‘breakthrough’ cancer treatments

Some argue the current system of subsidising drugs in Australia needs changing to accommodate new cancer therapies. But two recent drug listings show the current system is working perfectly well.
Most common childhood cancers are leukemia and Hodgkin lymphoma. Shutterstock

How poverty is killing Kenya’s children with cancer

Most children who have cancer live in the developing world where their survival rate is less than 25%. In Kenya awareness about childhood cancer is low and treatment isn’t always readily available.
Some people taking these drugs can see their cancer completely disappear – there’s nothing left to see on their x-rays. from www.shutterstock.com.au

Cancer immunotherapy drugs like Keytruda and Opdivo hold hope for some, but there’s still a way to go

Imagine being able to offer hope to people with cancers once thought untreatable. Checkpoint immune drugs like Opdivo and Keytruda lead this new era in treatment. But they don’t work for everyone.
Therapies on a nano scale rely on engineered nanoparticles designed to package and deliver drugs to exactly where they’re needed. from shutterstock.com

Explainer: what is nanomedicine and how can it improve childhood cancer treatment?

Nanoparticles are a form of transport for drugs and can go places drugs wouldn’t be able to go on their own. They make drug delivery more targeted, reducing collateral damage to healthy tissues.

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