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Articles sur Cytokines

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Addressing the increased risks of certain diseases among those with Down syndrome could help improve their quality of life. Halfpoint Images/Moment via Getty Images

Several Down syndrome features may be linked to a hyperactive antiviral immune response – new research

People with Down syndrome have an extra chromosome 21. Understanding the effects of those triplicated genes could help improve the health of those with Down syndrome and other medical conditions.
Bacteria (clusters of light pink, surrounded by larger magenta blood cells) can cause deadly infections, but overreactive immune responses can deliver the lethal blow. Scharvik/iStock via Getty Images Plus

Sepsis is one of the most expensive medical conditions in the world – new research clarifies how it can lead to cell death

An overactive immune response to infection can be deadly. Studying how one key player called tumor necrosis factor, or TNF, induces lethal immune responses could provide new treatment targets.
Killer T cells (green and red), or cytotoxic T cells, surround a cancer cell (blue, center). NICHD/J. Lippincott-Schwartz

Anti-cancer CAR-T therapy reengineers T cells to kill tumors – and researchers are expanding the limited types of cancer it can target

Immunotherapy has the potential to eliminate tumors, but works best for select patients. Engineering T cells to bypass cancer’s defenses could help expand treatment eligibility to more patients.
Dendritic cells (green) produce cytokines like IL-12, which can train T cells (pink) to attack tumors. Victor Segura Ibarra and Rita Serda/National Cancer Institute via Flickr

‘Masked’ cancer drug stealthily trains immune system to kill tumors while sparing healthy tissues, reducing treatment side effects

One promising cancer treatment has been in the works for decades, but severe side effects have kept it out of the clinic. A reengineered version may offer a way to safely harness its potent effects.
What would Darwin consider the best adaptation to protect against the coronavirus? rolbos / Getty Images

What does ‘survival of the fittest’ mean in the coronavirus pandemic? Look to the immune system

Who is most likely to survive an infection of the new coronavirus? Two immunologists explain that it is those who mount exactly the right immune response – not too weak, not too strong.
Eskymaks/Shutterstock

Can the menopause really be reversed?

Researchers at a fertility clinic in Athens appear to have reversed the menopause in a small group of women – but will the science stand up to scrutiny?

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