Virtually every medical therapy in use today owes its existence to animal experiments. But we can't assume what works in animals will in humans. And sometimes, the mismatch can be dangerous.
We still don't know what's behind four out of every five birth defects. But that can change.
The randomised controlled trial is touted as the gold standard in medical research. But its controlled laboratory conditions are far removed from the messy realities of life.
The MHRA has opened an inquiry on the once popular pregnancy test pills. Did they really cause birth defects in children born in the 1970s?
This was the year of the health review – mental health care, Medicare, private health insurance, the pharmacy industry ... and the list goes on. But how much movement was there on policy?
Thalidomide is notorious for causing death and disability but it – and its derivatives – are proving useful for conditions such as leprosy.
The thalidomide tragedy changed how medicines are viewed during pregnancy – not only by pregnant women, but also the wider community.
Tighter regulations of medicines and devices have prevented countless deaths and disabilities. But regulation can't always protect us from harm.
Thalidomide was responsible for one of the biggest drug disasters in history. It is making a comeback. But is Africa equipped to handle this controversial drug?
Reactions to the thalidomiders' difference contributed – and continue to contribute – to their negative well-being and deteriorating health.
Decades have passed and yet the issue of financial compensation for the remaining "survivors" of the thalidomide tragedy has, in many instances, remained unresolved.
Journalist-turned-lawyer Michael Magazanik worked on recent Australian thalidomide lawsuits. As part of our series on the drug, he spoke to Ian Freckelton about the book he wrote, based on the case.
Thalidomide's manufacturer, Chemie Grünenthal, marketed the drug as safe for pregnant women despite reports it was causing malformations in newborns. Why such blatant denial?
Sir Harold Evans talks to Richard Sambrook about The Sunday Times' moral campaign against thalidomide's manufacturers, the fight for political validation and the rise of investigative journalism.
Thalidomide was developed in an era of widespread enthusiasm – but little critical attention – for pharmaceutical therapies.
Thalidomide was marketed as a safe, sleep-inducing drug, but when taken during pregnancy it could cause severe birth defects.
Thalidomide caused thousands of spontaneous abortions and left more than 10,000 children severely disabled. What guarantee is there that the same thing can’t occur again today?
Documents reveal thalidomide's manufacturer was warned about possible harms as early as 1956.
A third of Australian women take medication while pregnant. So what's safe and what's not?
Research published today has found an association between commonly used antidepressants and birth defects. But pregnant women face greater harms from stopping their medication abruptly.