There are now hundreds of genetic tests that claim to predict the risk of various diseases. All that’s needed is a few drops of blood.
Individuals who carry the breast cancer genes _BRCA1_ or _BRCA2_ are often unaware of the fact. That suggests that physicians need a new way to apply DNA-based screens to identify those at risk.
Breast cancer type 1 (BRCA1) is a human tumor suppressor gene, found in all humans. Its protein, also called by the synonym BRCA1, is responsible for repairing DNA.
Mutations in BRCA genes are linked to the early onset of breast and ovarian cancers. But the effect of most mutations is unclear. Now new research can distinguish harmless from dangerous mutations.
By In The Light Photography/shutterstock.com
We now have the capacity to quickly and cheaply sequence an individual's genome and scour it for disease-causing genes. But how much, and what type, of information does a parent-to-be want to know?
Genetic testing for breast cancer gene mutations is now available. But it could lead to over treatment.
A genetics testing company recently won approval from the FDA to market a test that can identify a breast cancer gene mutation. But what are women supposed to do with that information? There's risk involved.
Tomas Lindahl, pictured here in the lab, along with Paul Modrich and Aziz Sancar, received the Nobel Prize for Chemistry.
The recipients of this year's Nobel Prize for Chemistry showed that DNA is far from static. Rather, it is bombarded by damaging forces, but our bodies know how to repair these precious strands.
BRCA1 and BRCA2 gene mutations prompted Angelina Jolie to have a preventative double mastectomy and surgery to remove both ovaries.
What if you could take a simple test to reveal your individual risk of developing a range of cancers and hundreds of other diseases?
Australia’s Federal Court last year rejected Ms D'Arcy’s appeal and ruled companies could patent genes they isolated.
The High Court challenge is the last resort for Ms D'Arcy's test case against companies patenting human genes and has implications for patients, clinicians and researchers.
Stopping breast cancer step by step.
It is well established that faults in the BRCA2 gene (and the BRCA1 gene that prompted actress Angelina Jolie to undergo a mastectomy) increase the risk of breast, ovarian, prostate and other cancers…
A gene patent means only the patent-holder has the right to undertake research and development involving that gene.
The Federal Court’s decision that gene patenting is permitted in Australia will have ramifications for all gene patents, even though the case involved only one gene associated with breast cancer. A gene…
The case was brought on behalf of cancer survivor Yvonne D'Arcy.
A Federal Court decision to allow gene patents could open the way for existing patents to be enforced more strongly in Australia…
Women with the BRCA1 mutation should have their ovaries removed before the age of 35 to reduce their risk of ovarian and…
Tamoxifen may offer hope for women with a gene mutation that puts them at a high risk of developing breast cancer.
Paloma León y Luismi Cavallé
Use of the anti-cancer drug Tamoxifen is associated with a dramatically reduced risk of developing a second breast tumour…
The decision may impact on an impending Australian appeal.
Image from shutterstock.com
All nine members of the US Supreme Court have ruled that isolated genetic material cannot be patented – unless the material is markedly different to what exists in nature. The court ruled against Myriad…
Angelina Jolie’s double mastectomy has sparked a series of reports about preventative surgery.
Following Hollywood actress Angelina Jolie’s revelation last week that she’d undergone a double mastectomy to prevent breast cancer, it has emerged that a 53-year-old man had his prostate removed after…
Angelina Jolie should be seen as a model for seeking information about her options and making a decision that best suited her.
Angelina Jolie’s recent announcement about her double mastectomy likely caused many women to think about their own chance of developing breast cancer. But before you rush off to have a bunch of possibly…