AMPK is normally a tumour suppressor. But once cancer arises, AMPK becomes a tumour promoter, enhancing the survival of cancer cells. Understanding this could help create drugs that inhibit AMPK.
Pancreatic cancer currently has one of the least optimistic prognosis, with just 5% of patients surviving five years after diagnosis. A recent study opens a door to hope.
Alex Trebek recently received news that he is in remission from pancreatic cancer.
Alex Trebek announced this week that his pancreatic cancer is in remission. A pancreatic cancer specialist explains the difficulties of the disease as well as new treatment advances.
A 12-week-old baby female macaque, named Grady, was born from frozen testicular tissue.
Oregon Health and Science University
Children with cancer not only endure chemotherapy or radiation treatment but they may also face infertility in adulthood. Now a new procedure, just proven in monkeys, may be close to use in humans.
Alex Trebek shown in 2006.
Reed Saxon/AP Photo
Pancreatic cancer has historically had among the lowest survival rates of any type of cancer. A recent study that looked at genomic changes reveals some possible clues.
Endocrine therapy is currently the most effective form of treatment for oestrogen-dependent breast cancer, but a significant proportion of patients relapse.
A new breast cancer test predicts whether a patient will benefit from endocrine therapy, allowing patients and their doctors to make better treatment decisions.
The Princess Margaret Cancer Centre in Toronto runs a Cancer Rehabilitation and Survivorship Program, which offers one-on-one consults and an eight-week group rehabilitation program for patients.
Multidisciplinary rehabilitation teams could help cancer survivors to recover from the toxic side-effects of their treatments and return to their lives.
Cancer treatment could be revolutionised by the discovery of the origin cells which divide first.
This is a model of the adenovirus type 5 which causes respiratory infections.
When you think of viruses, you might think of the horrible illnesses they cause, like flu or Ebola. But now researchers are learning how to use the unique traits of viruses to treat disease.
Different genes drive cancer growth in males and females.
Male and female tumors are different. Researchers are now hoping to exploit these sex-specific differences to treat brain cancer. This might improve survival for everyone.
There are lots of ways to support a friend through breast cancer. Sharing the journey is key, studies suggest.
People across the country show their support for breast cancer patients and survivors by wearing pink and raising money each October. A recent study of patients suggests ways to help all year.
Many cancer patients have chemotherapy after surgery, but not all of them actually need it.
We have no reliable way of knowing which patients' cancer will return after surgery, so often chemotherapy is given to mop up any remaining cancer cells that may have gone undetected.
Surviving breast cancer has been the biggest treatment goal until recent years, when attention began to turn to surviving well, as these three women appear to be.
While more women than ever are surviving breast cancer, they often do so with bad side effects. Studies are showing that physical therapy early in the post-treatment phase can help.
More than just a stomach bug.
Patients undergoing chemotherapy are at particular risk from food poisoning - but they aren't being made aware how critical food safety is at home.
Breast cancer tumours behave, and are treated, differently.
Headlines that 70% of women with breast cancer don't need chemo need to be heeded with caution: it's a very specific (but substantial) subtype that was studied.
We only know if a cancer has been cured in hindsight.
Photo by Kaylee Eden on Unsplash
A cancer is in remission when it can no longer be detected. But we only say it's cured when it hasn't come back for a certain time – and that differs for different cancers.
Circadian clocks regulate the timing of hundreds of processes in the cell, suggesting that matching medications with your biological clock could improve the outcome
Prostate cancer cell, viewed with a scanning electron microscope.
Cancer doesn't just grow uncontrollably. It has a smarter strategy than that.
A new silver-based compound that is less toxic with fewer side effects could hold the key to crippling cancer.
Collaborations between mathematicians, cancer biologists and clinical oncologists enable both rapid cost-effective testing of cancer drug combinations, and deeper understanding of cancer drug resistance.
Cancer is the second leading cause of death globally. Mathematicians have joined the fight, developing models to both test cancer drug combinations and understand chemotherapy drug resistance.