A genetic deficiency in males has been shown to encourage the onset of a common type of liver cancer and type 2 diabetes.
When the NCOA5 gene drops to a deficient level in male mice, a spontaneous reaction occurs. This produces cells that lead to hepatocellular carcinoma, a type of liver cancer that is two- to four-times more prevalent in males than females.
The researchers also found that male mice had occurrences of glucose intolerance when the gene was altered. Glucose intolerance is a pre-diabetic condition that increases the risk of Type 2 diabetes in humans.
Read more at Michigan State University