Monday’s medical myth: natural cancer therapies can’t harm you

One of the most misleading myths of modern medicine is that conventional cancer doctors reject “natural” therapies in favour of artificial or “unnatural” cancer treatments. This myth has contributed to the popularity of unproven, alternative cancer treatments. The truth is that oncologists and other…

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Natural does not necessarily equate to harmless. Nor does conventional equate to unnatural. Flickr/wine me up

One of the most misleading myths of modern medicine is that conventional cancer doctors reject “natural” therapies in favour of artificial or “unnatural” cancer treatments. This myth has contributed to the popularity of unproven, alternative cancer treatments.

The truth is that oncologists and other trained medical professionals involved in cancer care welcome and support effective cancer treatments in any form, provided there is evidence to show they can work and are safe.

Making assumptions about the benefits and harms of therapies according to whether or not they are natural is high-risk. For example, laetrile, an extract from apricot kernels, was for years promoted as a natural alternative therapy for cancer; yet it is utterly useless for treating cancer and can cause fatal cyanide poisoning.

The herb comfrey, also recommended as an alternative cancer treatment, actually causes cancer.

So natural does not necessarily equate to harmless. Nor does conventional necessarily equate to unnatural. Plenty of natural products are used in chemotherapy. These include extracts from the yew tree (docetaxel, paclitaxel), the opium and mandrake plants (epipodophyllotoxins) and from natural moulds that produce doxorubicin and related drugs, used effectively to treat breast cancer and lymphoma.

Some natural products used in conventional cancer medicine had for centuries been part of traditional folk remedies and have been adapted for modern use after being rigorously tested.

So the difference between alternative and conventional is not that one is natural and the other is not. It’s that conventional cancer treatments must be subjected to rigorous research before they can be recommended for use and prescribed by professional oncologists.

The highest level of research is the randomised control trial, which is only applied to a product after lengthy laboratory studies, preliminary testing and approval by an ethics committee made up of medical experts, ethicists and healthcare consumers.

A typical trial involves randomly selecting two groups of patients in large enough numbers to control for physical differences between them. One group receives the new treatment and the other group is given a different treatment or a placebo; the results are then compared. A trial is designed to show that any significant difference in patient outcomes can only be the result of the treatment being tested.

Oncologists will only prescribe treatments if they have been tested in this way and are found to be effective and safe.

A good example of this testing process on a natural derivative is the development of the drugs vincristine and vinblastine, extracted from the Madagascan periwinkle. Improved through continual clinical trials over 50 years, these so-called “vinca” alkaloids have been a key part of modern-day successes in curing childhood leukaemia and other cancers that were previously incurable.

A healthy diet can prevent cancer and assist people living with cancer, but it won’t cure cancer. donireewalker

Some alternative cancer therapists also promote fad diets, but there is no evidence to support this approach. A healthy diet can prevent cancer and assist people living with cancer. But diet will not cure cancer, which directly attacks the body’s cells in a highly destructive and relentless way.

Such a malignant disease can only be cured if the cancer cells are surgically removed before the cancer has spread or if they are destroyed with chemotherapy and/or radiotherapy.

Nor is there any evidence to support mind control in any form as a cancer therapy. Such a belief or expectation in many cases adds to a patient’s distress. Can you imagine the terrible trauma of being diagnosed with a potentially fatal cancer and told you can think your way to good health with a positive attitude?

The reality is, we have a limited lifespan; science does not have all the answers to our health needs. But we agree as a society that we should do what we can to increase life expectancy and improve health.

Over the past century, average Australian life expectancy has increased by almost 30 years, largely through a combination of improved infection control, sanitation, diet, immunology and many other advances in medical science.

The changes in medical practice and public policy that have improved our length and quality of life were guided by evidence of what works.

So we must let the evidence – not uninformed perceptions of what is natural – guide continuous improvements in cancer treatment.

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24 Comments sorted by

Comments on this article are now closed.

  1. Edward John Fearn

    Edward John Fearn is a Friend of The Conversation.

    Hypnotherapist and Naturopath

    Thank you Ray I found this article quite informative, I really don’t know why laetrile is still being promoted by some doctors as a cancer cure when there is not even weak supporting evidence. It’s also quite disconcerting that they also seem to broker loans with finance companies for their patients. Combine that with the fact they all seem to open up shop in Mexico should set off warning bells.
    A good source of information on evidence based CAM for integrative cancer support can be found here:
    http://www.cam-cancer.org/

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  2. James Walker

    logged in via Facebook

    Comfrey causes cancer...in rats. When they are force fed insanely high dosages.

    Granted turning to natural therapies to treat cancer is foolish: natural therapies are intended to assist the body, while cancer is the body attacking itself - so they will make the cancer stronger. Thus taking comfrey (or 'knitbone') would be suicidal for anyone with bone cancer. But it's hardly surprising that serious warnings are being ignored, when made when a remedy that has been used for centuries to successfully treat broken bones (and which now has scientific backing for this) is constantly being attacked.

    The latest is wanting topical treatments removed because rubbing the stuff into a cut could result in some getting into the blood stream. You *don't* massage a cut! Anyone dumb enough to do that is going to die no matter what you do.

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    1. Sue Ieraci

      Public hospital clinician

      In reply to James Walker

      It's hard to find good evidence for comfrey. It certainly has risks of adverse effects on the liver - including carcinogenesis.

      The studies I have found in relation to bone-healing use homeopathic comfrey - ie no comfrey at all.

      I found one study in a chiropractic journal looking at topical comfrey mixed in a cream for osteoarthritis - which apparently helped relieve pain and stiffness (possibly from the local massage and heat).

      james Walker - where is the work showing that comfrey affects bone healing at a cellular level - ie induces osteobalsts? I can't find any - do you have references?

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  3. Tom Hennessy

    Retired

    "laetrile, an extract from apricot kernels, was for years promoted as a natural alternative therapy for cancer; yet it is utterly useless for treating cancer and can cause fatal cyanide poisoning."

    Using logic.
    Cyanide is used in the mining industry because cyanide binds metal up allowing for it to be removed.
    "Although the affinity of cyanide for gold is such that it is extracted preferentially, cyanide will also form complexes with other metals from the ore, including copper, iron and zinc."
    Metal has been implicated in cancer , so much so , metal chelators are being used in cancer therapy to remove metal. Thusly , UNTIL PROVEN to NOT be a cancer killer , cyanide should not be regarded as , "useless" .
    Using logic.

    "Iron chelators possess potent anti-tumour activity"
    "Effectively inhibits oesophageal cancer growth in vitro and in vivo"

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    1. Susan Ruthenbeck

      Luftmensch

      In reply to Tom Hennessy

      "inhibits oesophageal cancer growth in vitro and in vivo"

      Many substances will kill cancer cells. It is a matter of balancing this property against the toxicity to the body generally. Cyanide IS an effective poison..that is generally known.

      Thank-you for the article Professor Lowenthal. The essential message is that evidence-based scientific medicine is just that. There are other potentially effective therapies 'out there' which are yet to be put through rigorous clinical trials.

      The point…

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    2. Sue Ieraci

      Public hospital clinician

      In reply to Tom Hennessy

      Cyanide is a very potent poison.

      Using logic.

      If you die from cyanide poisoning, oesophageal cancer is the least of your worries.

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    3. Tom Hennessy

      Retired

      In reply to Sue Ieraci

      The dose is the poison.
      http://en.wikipedia.org/wiki/The_dose_makes_the_poison
      Much like homeopathy , except different.
      Since there seems to be a 'movement' in the use of laetrile in cancer and scientific studies DO show the possible 'mode of operation' of the substance , then compared to drugs in cancer , IE: extremely dangerous and never hardly used to CURE cancer , then cyanide should not be considered "useless" WHEN unproven. Since it DOES 'complex metal'.
      "CHELATOR THERAPY : STABILITY CONSTANTS. OF TRANSITION METAL COMPLEXES"

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    4. Sue Ieraci

      Public hospital clinician

      In reply to Tom Hennessy

      "Much like homeopathy, except different."

      No, very different.

      Homeopathy = no detectable molecule of the alleged initial "remedy".

      Laeterile = poison.

      Cyanide toxicity is proven.

      Great internet searching, Mr Hennessy, but cyanide holds no promise at all as a cancer therapy.

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    5. Swetha Srinivasa Murali

      PhD Scholar at University of Sydney

      In reply to Tom Hennessy

      Tom, firstly, as a pharmacologist, I really hate people using the Paracelsus quote regarding dose out of context.

      Secondly, saying any chelator is okay to use is simply ridiculous. There are a variety of chelators, each with their own toxicity profiles. When there are much safer alternatives, there is no biological advantage in using a chelator with such high toxicity.

      Thirdly, any argument invoking homeopathy and 'homeopathic principles', I think, can safely be thrown out.

      Next time someone writes an articles making the point that there are effective drugs to be found in nature, it would be a good idea to not undermine yourself by trashing their work.

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    6. Tom Hennessy

      Retired

      In reply to Swetha Srinivasa Murali

      "it would be a good idea to not undermine yourself by trashing their work"

      I put in quotes the word used , "useless" , and argued the point , which is , using logic , cyanide should not be CONSIDERED useless UNTIL it has been PROVEN otherwise , just like arsenic.

      "Cyanates can control the sickle cell crisis."

      According to that , the dose , food derived cyanide , is considered to be THE factor why some do not manifest their sickle cell. I suppose if one fed them extreme doses of cyanate they might die , but , as evidenced , it seems a low dose doesn't kill them , it actually benefits them.
      Coincidentally , iron removal takes a sickle cell patient from 10 x 1 in hospital presentation. One might assume the cyanate complexes with iron and allows it to be removed.

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    7. Sue Ieraci

      Public hospital clinician

      In reply to Tom Hennessy

      Mr Hennessy - cyanates are not the same a cyanide, just like H2O is different to hydrogen and oxygen. Hydrofluoric acid is not the same as fluoride. Compounds are not the same as elements

      Ms Murali's point is apt.

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    8. Tom Hennessy

      Retired

      In reply to Sue Ieraci

      Actually I don't think she made a point. Cyanide doesn't complex and remove metals. And she is a scholar in pharmacology. Hell in a handcart.

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    9. Tom Hennessy

      Retired

      In reply to Tom Hennessy

      This describes the dose , cyanide from food.

      http://goodschoolfood.org/sicklecell.shtml

      "Agbai knew that manioc (cassava), indigenous to the West Indies as well as Central and South America, was a major food along with true yams (Dioscorea species) and a variety of beans, all contributing to high yet nonlethal plasma levels of thiocyanate in the population"

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    10. Tom Hennessy

      Retired

      In reply to Sue Ieraci

      "Thiocyanate isn't cyanide"

      There is no thiocyanate without cyanide.

      Cyanide complexes and reduces toxicity.

      "Cyanide offers some protection against selenium toxicity in rats , possibly through the formation of the SeCN ion"

      So , since your abilities have again become apparent , lack thereof , one must conclude your contributions are not really that contributory.

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    11. Sue Ieraci

      Public hospital clinician

      In reply to Tom Hennessy

      There is no water without hydrogen and oxygen, Mr Hennessy, and yet water is neither hydrogen nor oxygen.

      The majority of people poisoned by cyanide will die at the scene. It blocks the cytochrome oxidase system, causing cell hypoxia (cells can't perform oxidative phosphorylation).

      In the past. amyl nitrate was kept in emergency depts as an anti-dote, because it would form methaemoglobinaemia (dangerous in itself, but less so than cyanide). When amyl nitrate became an abused drug, it stopped being used for this purpose.

      The standard cyanide kit now contains sodium thiosulphate, which, if given early enough, can complex with the cyanide to form the safer compound thiocyanate, and be excreted.

      And guess what, Mr Hennessy - thioyanate is not cyanide.

      Thank you for helping me to continuously update my toxicology knowledge by correcting you.

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    12. Tom Hennessy

      Retired

      In reply to Sue Ieraci

      "thioyanate is not cyanide"

      Why don't you explain how thiocyanate is created without cyanide. It will update my chemistry knowledge.

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    13. Sue Ieraci

      Public hospital clinician

      In reply to Tom Hennessy

      Mr Hennessy - take this analogy. The combination of two hydrogen ions and one oxygen ion forms water, which is no longer either hydrogen or oxygen - it is a molecule of water. That is the difference between elements and compounds.

      Similarly, the combination of a carbon and two oxygens create a carbon dioxide molecule, which is no longer either carbon or oxygen, but a new compound.

      Thiocyanate is a molecule that contains a cyanide ion, but is not cyanide.

      Does that make it clearer?

      Here is a good article to update your chemistry knowledge:
      http://wiki.answers.com/Q/What_is_a_chemical_compound

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    14. In reply to Sue Ieraci

      Comment removed by moderator.

  4. Ben Greening

    logged in via Facebook

    Wow what a lot of generalised statements in one place.

    Representing natural medicine as being the lunatic fringe, and vice versa, novel line of argument, not.

    No properly educated natural medicine professional uses megadose therapy, and herbalists stick to the uses and dosages of the authorities (the BHP). Megadose comfrey and apricot kernels may be 'natural' but they aren't traditional. Not all treatments we use attack the cancer either, we are able to offer a huge amount of support and…

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    1. Sue Ieraci

      Public hospital clinician

      In reply to Ben Greening

      "I also think it's a problem when close minded oncologists seek to play god with their patient's lives and pretend they have all the answers. "

      Ben Greening - did you actually read the article?

      It's about how the toxicity of purported remedies doesn't depend on whether or not they are of "natural" origin. The author is not saying that the use of laeterile is traditional - he is saying that it is highly toxic, despite being "natural" in origin. He also says that other plant-derived therapies…

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  5. Peter Sommerville

    Scientist & Technologist

    Thank you Ray - in the context of the offerings on "The Conversation" this is exceptional. Having watched a close friend die whilst his wife administered "natural therapies" I appreciate the common sense approach you have advocated.

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  6. Pip Cornall

    Director Grace Gawler Institute

    Thanks Ray. Like you I’m regularly compelled to write about this topic, even at the risk of repeating myself, because I witness so much harm caused by so called natural cancer cures.

    Though not medically trained, in my role as a director of a cancer charity in Queensland, I'm continually confronted by the large numbers of cancer patients coming to us who have put their faith in 'natural medicines' or 'miracle diets' found on the internet or promoted by unethical entrepreneurs. If I wrote in detail…

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  7. Mark Amey

    logged in via Facebook

    Professor Lowenthal, thanks for a very informative article, which should be available to the general public, not just us 'Conversation' fans.

    My wife was diagnosed with breast cancer about seven years ago, at the same as a work colleague. My wife is very fortunate to have been treated with surgery, chemotherapy and radiotherapy, and, more recently, Herceptin, a medication which binds to a receptor on the cancer cells, inhibiting their growth. She continues to enjoy good health, work, etc.

    My colleague decided to avail herself of some 'waters' that were irradiated with special healing frequencies. The 'waters' obviously failed, and she had chemotherapy, around nine months later than she could (or should) have. Unfortunately, she didn't survive. There were absolutely no repercussions to the person who prescribed the 'radiation water'!

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