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New approach to treating type 2 diabetes

A new drug tested on rodents may help prevent the development of type 2 diabetes and reverse its progression.

The drug blocks signalling from a protein, known as vascular endothelial growth factor B (VEGF-B), which then prevents fat from accumulating around the heart and other muscles.

Researchers found the cells in these tissues were then able to respond to insulin again, resulting in normal blood glucose levels.

Read more at University of Melbourne

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2 Comments sorted by

  1. Monika Merkes

    Honorary Associate, Australian Institute for Primary Care & Ageing at La Trobe University

    "A new drug tested on [insert animal species] may help [insert prevent OR treat] [insert cancer OR HIV OR diabetes OR any other serious disease for which we haven't found a cure yet]. The drug [insert what it does in animals] etc. etc. ....."
    Why do we keep hearing/reading this, but rarely do we learn that one of these drugs tested in animals later leads to significant progress in curing human disease?
    Monkeys can be cured of HIV, mice can be cured of cancer and diabetes, but these treatments DO NOT work in humans. Because we are a different species. We are genetically, metabolically and anatomically different. More than 90% of new drugs fail in clinical trials http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2811%2960802-7/fulltext .

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