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Articles on Animal models

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As an animal model, the zebrafish offers many advantages that save researchers time and money. Uri Manor/NICHD via Flickr

Zebrafish are a scientist’s favorite for early-stage research – especially to study human blood disorders

Of the many qualities that make the zebrafish a model organism, the fact that it shares 70% of the genes humans have makes it an ideal candidate for developmental biology research.
The lung-on-a-chip can mimic both the physical and mechanical qualities of a human lung. Wyss Institute for Biologically Inspired Engineering, Harvard University/Flickr

Organ-on-a-chip models allow researchers to conduct studies closer to real-life conditions – and possibly grease the drug development pipeline

Successes in the lab mostly don’t translate to people. Research models that better mimic the human body could close the gap.
Rhesus macaques experience an aging process similar to people’s. Goddard Photography/E+ via Getty Images

Expanding Alzheimer’s research with primates could overcome the problem with treatments that show promise in mice but don’t help humans

Nonhuman primates like rhesus monkeys share certain characteristics with people that may make them better study subjects than mice for research on neurodegenerative diseases.
A single brilliant insight is only part of the story of how diabetes became a manageable disease. Douglas Grundy/Three Lions via Getty Images

Insulin was discovered 100 years ago – but it took a lot more than one scientific breakthrough to get a diabetes treatment to patients

A biomedical engineer explains the basic research that led to the discovery of insulin and its transformation into a lifesaving treatment for millions of people with diabetes.
Whether it’s birds in a flock or drivers in traffic, agent-based modelling can describe complex phenomena by applying a simple set of rules to each individual’s behaviour. Barry Sweet/EPA

Traffic is complex, but modelling using deceptively simple rules can help unravel what’s going on

By identifying and applying the key rules governing the behaviour of each individual, agent-based modelling offers insights into complex phenomena like traffic jams and flocking.
What is Ebola? Emilia Stasiak

Do our genes determine whether we survive Ebola?

Despite killing a majority of people it infects, some patients survive the onslaught of Ebola virus. What gives them this resistance, ask Michael Katze, professor of microbiology, and colleagues from the…

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