The Histopathology & Tissue Shared Resource (HTSR) is Georgetown Lombardi's resource for accessing human tissue for translational research and provides comprehensive, high quality laboratory and interpretive pathology services. The HTSR consents for, collects and distributes fresh- and formalin-fixed paraffin embedded tissue as well as provides technical and pathological support for investigator-driven collection protocols including the novel conditionally reprogrammed cells program. The HTSR also coordinates with the company Indivumed for the collection of high-quality biospecimens including matching fresh frozen and formalin fixed tissues, serum, plasma, urine and comprehensive clinical data. HTSR Co-Director Brent Harris, MD, PhD, provides comprehensive pathology services with a speciality in neuropathology. Under the direction of HTSR Co-Director Deborah Berry, PhD, the Histopathology Laboratory provides comprehensive histology services including necropsy, tissue processing, microtomy, staining, immunohistochemistry, laser capture micro-dissection and tissue microarray construction, staining and high-throughput analysis. In addition, the HTSR provides expert technical support, consultation services and educational support and training for users.