Igor Vorechovsky

Dr Igor Vorechovsky is Principal Research Fellow within Medicine at the University of Southampton. Dr Vorechovsky joined the Faculty of Medicine in 2002 as a Lecturer.

Why do we have genes in pieces? This arrangement greatly contributes to human morbidity.

Having graduated in medicine from the Purkynje University Brno, he was trained in general Paediatrics and specialised in Clinical Genetics. He completed his PhD 1989 in molecular genetics. He held clinical or research positions in the Institute of Child Health, Paterson Institute, Karolinska Institute and academic positions in UCL and Southampton University.

Dr Vorechovsky leads a group that investigates molecular mechanisms of predisposition to genetic disease at the level of RNA processing and their repair using non-genetic means. His past achievements include, for example, isolation of the gene for the first described immunodeficiency X-linked agammaglobulinaemia (Nature 361:226-233, Science 261:355-368) and identification of genes and critical mutations underlying several cancer-predisposing genetic disorders (Cell 85: 841-851, Nature Genetics 17:96-99). He is a co-author of >100 peer-reviewed articles, cited altogether >5,000x. Potential students, post-doctoral scientists or clinician scientists who are interested in joining his group are encouraged to contact Dr Vorechovsky.