Weihong Lin

Our lab research is focused on understanding the neurobiological aspects of chemical sensory systems in the nose, specifically mechanisms of sensory detection and functional maintenance. We use transgenic and genetically modified animals and multiple experimental approaches, including intracellular calcium imaging, electrophysiological recordings, immunolabeling, molecular analyses, and behavioral assays in our study. We hope to provide knowledge about: 1) sensory detection of certain chemical substances, such as flavors and other constituents in electronic cigarettes; 2) modulatory networks that adaptively maintain olfactory functions; and 3) environmental exposure-induced sensory dysfunction and associated behavioral deficits.