Treating depression ethically requires more than drugs

Spot the problem in this scenario. Richard* is stressed. While he’s a high-flyer (a Rhodes Scholar no less), he’s under the pump at work and has just moved his family across nations. The job is taking more than it’s giving back. He’s in a dark place – very down, unmotivated, ill-humoured and lacking…

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Drugs treat symptoms but do nothing to help people navigate depression. Shutterstock

Spot the problem in this scenario. Richard* is stressed. While he’s a high-flyer (a Rhodes Scholar no less), he’s under the pump at work and has just moved his family across nations. The job is taking more than it’s giving back. He’s in a dark place – very down, unmotivated, ill-humoured and lacking energy – so oblivion seems enticing. Worryingly, he also has a family history of depression.

Richard visits his family doctor who refers him to a psychiatrist. So far, this is unremarkable – as depression management goes.

With relief, Richard enters the psychiatrist’s plush rooms, sighs, and prepares to unburden himself and submit to wise counsel. But he’s in for a surprise. Within minutes he’s told he has depression, needs medication, and will likely do so for life. He leaves with sample pack of antidepressants in hand, and troubles still firmly packed in kit bag.

If you’re like me, you see the problem quickly. Richard, and around 70% of the people who share his diagnosis, can implicate a psychosocial stressor in the genesis of his depression. But his doctor has failed to identify and address it, even though stressor-focused treatments are available.

Drug-free alternatives

Evidence-based psychotherapy, in particular cognitive behaviour therapy (CBT), is as effective as medication in the common, lesser grades of depression. You read that correctly – CBT is as good as drugs at relieving the lowered mood, hopelessness, fatigue, guilt, and poor concentration that figure in the depressive diagnostic checklist.

And not only does psychotherapy reduce psychic distress, it also tackles stressors. In addition, CBT tutors healthy scepticism about the negative perceptions that pepper the depressive psychological landscape. Such ideas cause undue pessimism and arise, almost always, from biased information processing. Challenging negative thoughts is a critical element in the therapeutic success of CBT.

Incredibly, doctors who fail to unearth and address stressful life events, or guide a stance of scepticism to negative thinking, do nothing untoward. While recent guidelines laudably embrace a broader role for psychotherapy, depression initiative beyondblue still cites a publication that concludes, because drugs and psychotherapy are equally effective, really, either will do fine. As the authors of that paper state, it’s “not so much what you do but that you keep doing it”.

But is it really all right to just give people antidepressants? Does a doctor have a duty to do more, and provide psychotherapy?

For any other illness…

Evidence-based psychotherapy is as effective as medication for treating most cases of depression. Michael Thomas Angelo

Try this thought experiment. You have abdominal pain and visit your doctor, who diagnoses gallstones and recommends an operation. You become increasingly anxious, agitated, and ultimately morose at the prospect of surgery. But the doctor has a pill for that – take an antidepressant and your fears will fall away so that you can bravely front up to surgery.

This scenario is laughable, of course. A doctor would never recommend antidepressants to foster acceptance of an unpalatable circumstance. Rather, the physician would explore your fears, determine what aspects of surgery concern you, and offer information about the pre- and post-operative processes.

In essence, the doctor would provide you with information that is material to your decision about surgery, enabling you to cope with your new circumstance and to work out which course is best. And in doing so your doctor conforms to an entrenched moral duty – to promote patient autonomy, that is, the ability to self-determine based on information that is critical to interests.

But, despite respect for autonomy being embedded squarely in the moral firmament of informed consent, it seems alien to many physicians that information, not just about treatment but that results from it could also be material.

Richard will, in all likelihood, believe it material to understand which stressor caused his depression, how best to address it, and how to simultaneously deal with his relentless negative thinking. To glean this, he needs psychotherapy, not just information about it.

And doctors know this. They already promote autonomy through a range of treatment regimes. Specialists in drug and alcohol rehabilitation supply crucial facts about limiting substance use, nutrition consultants advise overweight patients to diet and exercise, hypertension specialists provide strategies for reducing salt intake, and so on.

In each case, a treatment is recommended not just because it’s effective, but because it provides information material to crucial life choices.

And this is precisely why evidence-based psychotherapy ought to be provided to people with depression. Drugs may treat symptoms but they do nothing to help people navigate depression, appraise and manage stressors, or critique the validity of their negative thoughts. A prescription for antidepressants might fulfil a physician’s clinical duty of care on current guidelines, but drugs alone fall short in the moral domain.

What Richard did

Richard opted for the DIY solution. Luckily for him, he had a formidable analytical arsenal at his disposal, and his critical faculties had not been fatally routed. He rounded on his job as a noxious influence in his life and bravely resigned, to the amazement of his boss. The depression lifted, sans medication, in less than a month.

Recently, the black dog scratched at his door again. This time he was prepared, and confidently asked his new boss to cut back his workload a little. Most people are not endowed with such self-possession. What people with depression need are doctors prepared to pay more than lip service to autonomy and to provide psychotherapy in those common grades where evidence supports its use.

*Not his real name

Paul Biegler is the author of The Ethical Treatment of Depression: Autonomy through Psychotherapy (MIT Press 2011), which won the Australian Museum Eureka Prize for Research in Ethics.

If you think you may be experiencing depression or another mental health problem, please contact your general practitioner or in Australia, contact Lifeline 13 11 14 for support, beyondblue 1300 22 4636 or SANE Australia for information.

This is the second article in our short series on depression. Click on the links below to read the other articles:

Part one – Explainer: what is depression?

Part three – Predicting the risk of depressive disorder – promises and pitfalls

Part four – The science of interpreting common symbols in dreams

Part five – Genetic testing for depression creates an ethical minefield

Part six – Are antidepressants over-prescribed in Australia?

Join the conversation

36 Comments sorted by

  1. Craig Minns

    Self-employed

    I suffered a severe reactive depression a few years ago which was very debilitating. I was offered drugs by a GP (Cipramil), but I never used them, despite purchasing a pack. I saw a psychiatrist who basically said "It's reactive, you'll probably just get over it once the stressor isgone" and he was right.

    However, nobody except that psychiatrist (who charges a great deal of money) was interested in underlying causes, or in hearing about stressors that might be exacerbating the situation.

    If GPs are to offer mental health services at all, perhaps it should be limited to referral to a more-qualified specialist for proper evaluation rather than prescribing drugs?

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    1. Jake Kirk

      Student (Pharmacology major)

      In reply to Craig Minns

      I think it's important to note anti-depressants, whilst often called "happy-pills" literally aren't. Something like ecstasy or even alcohol will make anyone happy and they work on quite a different mechanism.

      Antidepressants correct a problem of a biological nature, if it didn't exist in the first place, they obviously can't fix anything.

      For some people, especially those with mild depression, a negative outlook or a legitimately bad life event (getting divorced, etc) is what makes them depressed…

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    2. Jake Kirk

      Student (Pharmacology major)

      In reply to Jake Kirk

      Seem to cant edit my comment but this is why talk therapy is also essential, for those anti-depressants for one reason or another, just don't work for.

      Different studies have produced different success rate but total remission seems to hover around 50-75%. Antidepressants often need to be swapped, for some people the first one wont work. Of those people, the second one will work for most, not all. For those left, the third will work for the majority of those as well and so on (if not total remission at least decent relief).

      This is at least partly a design problem. The idea of serotonin imbalance causing depression isn't wholly true, we know this for a fact now. We know antidepressants work but we're not exactly sure how. It's that last part that makes it hard to create new treatments too.

      Id like to think most GP's would (indeed, should if appropriate) offer the option of medicare subsidised psychologist visits along with medication.

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    3. Sue Ieraci

      Public hospital clinician

      In reply to Jake Kirk

      You make an important point, Jake. Not all depression is a situational reaction, or amenable to change in life circumstances, or a different self-talk approach. Some depression is just a biological illness.

      We need to get over the post-modernist form of PC that categorises pharmacological treatment as "bad" and talking therapy as "good".

      Talking does not work well for severe disease, and is very long and slow. Many people with severe disease can;t engage in any form of talking therapy until…

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  2. Diana Taylor

    retired psychotherapist

    There are two distinct precursors to depression - psychological and neurological. Much of the debate about the effectiveness of CBT versus drugs fails to take that into account. I battled for years with CBT, with little effect. I needed the drugs, and still do. For me the drugs are highly effective. I also know people for whom the drugs were disruptive and who benefited greatly from CBT.

    My own view is that it is a mistake to call both these afflictions 'depression'. At least any article or research paper discussing depression should clearly differentiate between the two forms of depression arising from the two different precursors. Since one precursor will affect the other, it is not easy to identity which is the primary factor. However, that is not a good excuse for not making and effort.

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    1. Meg Thornton

      Dilletante

      In reply to Diana Taylor

      Oddly enough, I'm in the reverse boat - I've tried the medications, and while they help for a bit, they don't really do anything on their own. I can still be deeply depressed while taking antidepressants religiously every single day. For me, the therapy works because it provides me with an objective, outside-based look at what's happening in my head - basically if I've got someone else telling me that "yes, that is a depressive thought process and here's where it's going off the tracks", I find…

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    2. Jake Kirk

      Student (Pharmacology major)

      In reply to Diana Taylor

      It's true that biological problems can precipitate depression. Your brain is where all your perceptions and feelings arise, so a problem with the brain can cause a problem with these.

      However, it (quite remarkably) can work in reverse. Psychological states can cause biological damage. It's been shown that high levels of stress along with the corresponding hormones your body spits out in response (like cortisol) can alter neural function. Of course, to a person who is depressed for psychological or situational reasons, this is just adding insult to injury.

      If you're depressed because you're isolated or you lost someone significant, it just might have the potential to run backwards and cause a biological issue. That's why antidepressants are still a crucial treatment method.

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  3. Mister A

    Mental Health Advocate

    What an excellent article. I may get way off track here, but let me tell you a little bit about the mental health system in NSW. I've been working in mental health for 20 years and I am despairing at what we have created, a model dominated by presciption writing. It breaks my heart. I watch psychiatrists who barely listen to their patients, nurses who sit around reading novels and playing on computers, psychologists who are only interested in seeing patients if they can include them in some research…

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    1. Addy

      logged in via Twitter

      In reply to Mister A

      This is quite possibly the greatest comment I've read on this website.

      I cannot agree more with what you've said, though I do believe the issues you talk about are not limited to the NSW Mental Health system but occur nationwide (from direct personal experience, VIC, NSW and NT) as a result of badly funded, badly planned mental health policies.

      Everything you have written rings true, and I have many examples of being treated in a condescending and patronising way by those in the MH profession…

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    2. Lyndon Gordon

      PHD candidate at University of South Australia

      In reply to Mister A

      Great response, highlighting the sociological (often very oppressive) contexts in which people with mental health issues experience when seeking or recieving help. The article did skip over the dreadful conditions of the tertiary mental health sector in Australia - which is understandble given the focus on advocating for non-drug treatments for depression. I have been in a few public mental health units in hospitals as part of my social work qualification, and I saw many of the points you made in your response.
      The author of the article did importnantly discuss how individualistic drug treatments can be, potentially blaming the victim for their mental health issues, whilst the cause (in this case a overworked work environment) goes by un questioned and un changed. However, the white elephant of the dreadful mental health services in Australia always needs to be recognised and im so pleased that Mister A was able to articulate that so well.

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    3. Mister A

      Mental Health Advocate

      In reply to Addy

      Dear Addy,

      How sad and tragic. I'm so sorry to hear of your experience. Too often people are admitted inappropriately (a whole other issue) while people who genuinely need help are not admitted, as in your case.

      When I worked on a Crisis Team with a Community Mental Health service in Sydney it was not unusual for me to spend hours and hours in the ED with a client waiting for them to be assessed and advocating on their behalf for an admission and be turned away in the end. It was infuriating that even as a clinician myself I couldn't get help.

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    4. Ben Mullings

      logged in via Facebook

      In reply to Mister A

      Some great observations there Mister A. I agree.

      Just one point though.. the statement that "nurses and psychologists and social workers and OT's don't require any formal training in mental health to get a job in mental health" is not actually true. At least not for psychologists, where the basic training standard is 4 years at university, plus an additional 2 years of supervised practice in the field. A large proportion of psychologists do go on to undertake additional post-graduate training, with many focusing on a mental health domain of the profession.

      Some go on to specialise in delivering psychotherapy for mental health conditions (e.g., Counselling Psychologists and Clinical Psychologists). It doesn't sound like you come across many of those type of psychologists where you work though, which is a concern. I wonder if this is because not enough funding is dedicated to the role, or if selection processes are just not identifying the right type of psychologists?

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    5. john mills

      john mills is a Friend of The Conversation.

      artist

      In reply to Mister A

      Spot on MR A, counsellors /psychologists in every ward, every day, offering an ear and guidance, encouragement, a picture on the door, and a pad to put your name on for a visit, also small and large cognitive group discussions twice a week, a collective, connected, and acknowledged approach to the wellness of all, each and every patient, staff as well as counsellors/psychologists and the ones who probably need it just as much, the psychiatrists.
      We all need to find out and care about ourselves…

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  4. Cat Mack

    logged in via Facebook

    Insightful article. I noticed the local GP prescribing antidepressants to my elderly mother - although her depression is clearly the result of her circumstances. (An entirely rational response it seems to me)

    There are still far too many - pop a pill - treatments from doctors who are unwilling to take the time to see what the real problem is - and offer approaches to dealing with the circumstances.

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  5. Steven Rudolphy

    Part Time Senior Lecturer in General Practice (Cairns Campus) at James Cook University

    Do academics ever actually talk to GPs. We are busy folk so it may be difficult to. We despite our seeming ineptness (if you read this website) seem to have people queuing up to see us.

    Up to about 6 years ago GPs did give patients antidepressants with psychological support, it frankly was not very good. It went by the name of supportive psychotherapy because most of us had not trained in CBT and most patients could not afford to see the psychologists who were ( though more about this later…

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    1. Sam Jandwich

      Policy Analyst

      In reply to Steven Rudolphy

      Steven - yes this was my reaction to the article as well. There are a number of complicating factors to this issue which need to be addressed in a more comprehensive way than the article attempts.

      Firstly we probably have to raise the concept of "efficiency" as that seems to me the best way to describe the tendency for drug treatment to be the preferred first line of defence. CBT takes time, it is significantly more expensive than drug therapy, and it takes commitment from the patient as well…

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    2. Steven Rudolphy

      Part Time Senior Lecturer in General Practice (Cairns Campus) at James Cook University

      In reply to Sam Jandwich

      The concept of thinly spread psychiatrists spending weeks administering CBT to patients is of course risable. Psychologists are somewhat more plentiful and cheaper and leave doctors free to diagnose and prescribe drugs to psychotic patients rather than get caught up in the sea of neurosis that exists. (psychosis and neurosis are medical terms)

      As I wrote before this article shows basic lack of understanding of the real life health system which 10 minute chat with a clinician would have given some perspective.

      Also why do you hide behind a pseudonym

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    3. Ben Mullings

      logged in via Facebook

      In reply to Steven Rudolphy

      There are a wide range of psychological interventions that fall under the umbrella term of Cognitive Behaviour Therapy (CBT). It also often takes a while for a patient to understand how the CBT treatment approach works. Therapist often need to negotiate in the working relationship with a patient how that process of psychological change fits with the patient's expectations about treatment and recovery. Without sensitively managing that process, we often end up with disagreement and resistance to the…

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  6. Dennis Alexander

    logged in via LinkedIn

    I wonder if there is research on the relative effectiveness of other forms of psychotherapy than CBT.
    Also, as I understand it, there has been somework done in accrediting GPs to provide CBT. If so, it would be useful to get some data on relative effectiveness of GP CBT and Psychiatrist CBT, with and without drugs.

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    1. Steven Rudolphy

      Part Time Senior Lecturer in General Practice (Cairns Campus) at James Cook University

      In reply to Dennis Alexander

      Cost effectiveness is the problem psychiatrist around $250 per hour GP much higher overheads nurses reception etc $250 per hour, psychologists $120 p/h. Unlike our health minister realise these are fees before overheads which run at 35 to 50%.

      Unless you want user pays or pay s lot more tax psychologists should be doing the CBT or other appropriate therapy.

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    2. Gil Anaf

      Psychiatrist, Senior Clinical Lecturer, Adelaide University

      In reply to Dennis Alexander

      Yes, research does exist. An article in Psychotherapy Research 1998 by Ablon & Jones compared outcomes of CBT vs dynamic therapy. The Gottingen study of 2005 by Leichsenring et al looked at the effectiveness of psychoanalytic approaches, as did a study by Sandell (2000) in the Int Journal Psychoanalysis. Research is always ongoing in this field.

      There is a lot of research out there, including that which negates the notion that it costs too much to treat patients intensively. Providing such treatment saves the community money in other medical expenses, as research shows. Not that policy makers want to hear that.

      In my experience, upskilling GPs has sometimes led to some great difficulties in their providing CBT; usually because they have no time to appreciate the limitations of the approach, which can then lead to blaming the patient for lack of progress.

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  7. Gil Anaf

    Psychiatrist, Senior Clinical Lecturer, Adelaide University

    It might be fairly argued that the problem "Richard" had was that he was in the all too common position of finding that neither his GP nor his psychiatrist talked to him. That kind of "talking", which concerns itself more with understanding distress in order to find solutions, rather than confining itself to technocratic issues of diagnosis and evidence based treatment has become less available. In my view, that in turn has a lot to do with medico-political issues that are generally not known about…

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  8. Steven Rudolphy

    Part Time Senior Lecturer in General Practice (Cairns Campus) at James Cook University

    Reading the replies here it strikes me a couple of definitions may be useful:

    Clinical Psychologist. A person who has completed a degree in psychology and at least 2 years of supervised practice or a Masters degree in psychology.They have trained in treatments that do not involve drugs. They cannot prescribe drugs.

    Psychiatrist. A medical doctor who has trained in the speciality of Mental Health/psychologist taking 5-7 years of post graduate training to become a consultant/ specialist. They are specifically trained to make diagnoses ( a psychologist can too) and are able to prescribe medication.

    There are a lot of psychologists and not a lot of psychiatrists. Psychiatrists generally earn more than psychologists.

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    1. Gil Anaf

      Psychiatrist, Senior Clinical Lecturer, Adelaide University

      In reply to Steven Rudolphy

      As a recent post comments, it's horses for courses, different patients need different things. The definitions seemingly suggest a focus on money & expense (to patients & taxpayers). While that's clearly important, what gets left out when one reduces things to simple terms is complexity. Patients can be complex. Psychiatrists used to have a very broad based training that allowed them to not only diagnose, but treat, complex issues. It's a mistake to divide the professions into those that diagnose, and those that treat. As I said in another post, providing complex treatment actually reduces costs to taxpayers; the research shows that quite clearly.

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  9. Sue Ieraci

    Public hospital clinician

    "Evidence-based psychotherapy, in particular cognitive behaviour therapy (CBT), is as effective as medication in the common, lesser grades of depression..."

    This is certainly supported by good research. What is not often mentioned, however, is that CBT takes a long time to work, is very expensive and is very operator-dependent. Modern anti-depressants are safe, take a few weeks to work, and don't rely on repeated long visits with a therapist. Horses for courses.

    The other thing that is not clarified by this article is the difference between mild to moderate depressive symptoms that are stimulated, or worsened, by life circumstances or bad habits of thought, as against more severe depressive illness that has a familial tendency and is independent of life events. Not all depression is reactive.

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    1. Gillian Ray-Barruel

      Senior Research Assistant at Griffith University

      In reply to Sue Ieraci

      I completely agree with Sue's comments. Having experience with both CBT and medication, personally and with family members, I would say that both have a place in treatment. But CBT IS expensive and time-consuming, and not every practitioner is equal.

      What isn't mentioned in this article is ANXIETY, which is also a huge problem in society and one that anti-depressants (and CBT) are also useful in addressing. Many people are prescribed SSRIs for anxiety, rather than depression, but the article does…

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  10. Steven Rudolphy

    Part Time Senior Lecturer in General Practice (Cairns Campus) at James Cook University

    For the 3rd quarter of 2012 there were 381890 Medicare rebated consultations between psychologists and patients ( Medicare items 80000 to 80170 searched on the Medcare Australia website https://www.medicareaustralia.gov.au/statistics/mbs_item.shtml ) Patients previously were limited to 12 sessions in a calendar year that has been reduced to 10. All of these consultations have to be initiated by a doctor the majority are GPs to be able to claim a Medicare rebate.

    To give the impression that doctors hand out antidepressants without offering psychological support is at best misleading. Frankly if The Conversation has any credibility this article should be withdrawn and an apology made.

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    1. Gil Anaf

      Psychiatrist, Senior Clinical Lecturer, Adelaide University

      In reply to Steven Rudolphy

      It seems to me that the breadth & nature of the various posts and opinions, whether misleading or biased or anything else, at the very least demonstrates what an alive and ill-understood issue the whole area is. For that reason, I think the article should NOT be withdrawn.

      Psychiatrists were indeed described, by patients, in an old issue of Res Publica as unpopular precisely because they were seen as prescribing first and talking second. Some GPs do the same. This needs airing. I can't see why an apology is needed if these are (unpleasant) facts.

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    2. Craig Minns

      Self-employed

      In reply to Steven Rudolphy

      I paid for two psychologist visits myself, at $125 a shot back in 2004 with no result, as both she and I acknowledged. I also paid well over $1k for a single psychiatrist's visit and report, which took less than 10 minutes, but which was extremely useful, where the psychologist's interventions had been useless.

      None of that was paid for by anyone other than me, because I was feeling lousy and I am not inured to feeling that way.

      My impression, from two GPs in different practises, was that dispensing medicaments was their standard response. Doing a more complex analysis was neither within their skill-set, nor would it be paid for.

      Offer a "panacaea and piss-off" approach and bank the proceeds.

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  11. Phoebe Ledford

    Lawyer, Writer & Small Business Owner

    I just wanted to weigh in from a patient’s perspective, and to add to a comment made in response to Part 1 of this series regarding insurance.

    I identified very heavily with Richard* – for the most part I felt like the article could have been written about me. I had a very similar experience with my doctors except that I asked to be referred to a psychiatrist (one who had been recommended to me, at my request, by my brother’s psychiatrist). Yes, I had the family history as well, so I knew I…

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  12. Theo Pertsinidis

    Theo Pertsinidis is a Friend of The Conversation.

    ALP voter

    Speaking as a patient diagnosed with a mental illness and a full Disability Support Pension for the last ten years...

    Cognitive Behavioural Therapy, medication, healthy food, exercise, family support and understanding, and social inclusion has eased my condition.

    My main problem is I 'hear voices'.

    The remaining piece of the puzzle is participating in policy design.

    Most of the available information on mental health has been written
    by mental health professionals, mental health charities…

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  13. Ben Mullings

    logged in via Facebook

    The above article is a timely reminder of the need for mental health care policies based on research evidence. At the beginning of this year the Australian Federal Government cut public access to psychological treatment via Medicare to 10 appointments with no exceptions. The research shows that even with the most brief forms of therapy, such as CBT and IPT (mentioned above), the recommended minimum is 15 to 20 appointments. At ten sessions, we know that only around a third of people will show clinically…

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  14. Lydia Bridges

    logged in via Facebook

    This is a wonderful blog. Thank you for sharing this. I believe that it is important the the surgeon or the physician should explain very well the procedure that his or her client will under go. This will lessen its anxiety if she knows exactly what is going to happen.

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