Human challenge studies can be useful to test new vaccines and are increasingly being used internationally. Yet there are several ethical issues to consider.
Deliberately infecting people with a disease-causing agent as part of carefully considered medical research can be ethically acceptable or even necessary.
CDC/ James Gathany
Given the high burden of malaria in sub-Saharan Africa, a partially effective vaccine is considered better than none.
High magnification view of mosquito pupae and larvae underwater.
7th Son Studio/shutterstock
Researchers have tried unsuccessfully for decades to develop a malaria vaccine. Now a new approach, showing promise in mice, suggests it is possible to block mosquitoes from spreading the disease.
Scientists analysing data at the South-South Malaria Research Partnership project laboratory in Kenya.
Progress in malaria control has stalled. Research towards an effective vaccine is underway.
Baringo county and other areas on the western side of Kenya are struggling to reduce their seasonal malaria caseloads.
Most malaria cases and deaths occur in sub-Saharan Africa.
After an exceptional period of success in global malaria control, the progress has stalled. New strategies are needed to suit a variety of transmission patterns.
A malaria vaccine will be piloted in Ghana, Kenya and Malawi to assess its suitability.
Stronger malaria prevention like a vaccine is urgently needed for effective response in endemic regions.
Public health campaigns in malaria prone areas should increase.
The link between taking iron supplements and the increased risk of contracting malaria is a complex one.
Anopheles Gambiae, one of three mosquitoes found in Africa that transmit malaria.
The irritating buzz that rings in your ear in the dead of the night comes from an insect barely traceable with your naked eye. Here are a few facts worth knowing about the mosquito.
A doctor observes mosquitoes to better understand the malaria parasite which has been developing a resistance to the anti-malarial drugs.
Across the world scientists are trying to find a new drug that the malaria carrying parasite will struggle to develop a resistance to.
A young girl plays inside a mosquito net in Kibera, Nairobi.
Several countries within southern Africa are on the brink of eliminating malaria. But there are several challenges ahead.
Senegalese women treat mosquito nets with insecticides at a medical clinic in Northern Senegal.
As the World Health Organisation disbands the Roll Back Malaria secretariat, the focus is on the new malaria programme and whether it will have the same successes.
Malaria prevention is going beyond the mosquito net.
The announcement that GlaxoSmithKline (GSK) aims to register a malaria vaccine came on the same day Peter Higgs and Francois Englert were awarded the Nobel prize in physics for predicting the existence…