After the failure of multiple drug trials the outlook for an Alzheimer's drug is bleak. This shouldn't be a surprise. We don't know the cause or even how to diagnose the disease.
Protein tangles have been blamed for causing Alzheimer's – but drugs that target them keep failing.
Not all drug development needs to start from scratch. Sometimes researchers discover that a drug developed for one disease can be used for another. Here a cancer drug may show promise for dementia.
Our ability to smell is a function of the brain, so it makes sense that an impaired sense of smell can point to cognitive decline. The good news is training our noses may be effective.
When nerve cells in the brain pass electrical signals to each other, they create tiny electric fields that can be sensed from outside the skull.
Many pieces leading to Alzheimer's disease have been identified. To put the pieces together, one scholar argues that the government should launch a Manhattan Project-scale effort to find a cure.
We were the first to make the connection between P. gingivalis and fully diagnosed Alzheimer’s disease. While evidence of a link is growing, it must be interpreted in context.
Research is revealing many ways in which we can reduce our dementia risks -- from eating a Mediterranean diet and exercising, to playing games and studying for degrees.
Research milestones in the study of memory may help us find solutions to memory disorders like Alzheimer's or recovery from brain trauma.
Air pollution is bad for our heart and lung health – and a new study says it may be bad for brain health, too.
Biological research can inspire technological innovation. Also, software that models computer networks can inform health care for patients with neurological disorders.
The Trump administration has banned NIH researchers from using fetal tissue. The tissue is an essential tool for scientists investigating diseases ranging from Alzheimer's to Zika virus infections.
People with Down syndrome are at much higher risk of dementia than the general population. Knowing when cognitive changes start is critical for developing new drugs.
A new type of drug blocks the destruction of neurons in the eye, preventing blindness. The researchers hope that the same therapy can be applied to other common neurodegenerative diseases.
From aggressive patients with Alzheimer's to frustrated caregivers, dementia is increasingly entwined with violence in private homes and residential facilities.
With the World Chess Championship set to begin Nov. 9 in London, Alexey Root, who teaches online courses about chess in education, tackles some myths and unknowns about the royal game.
Higher education for seniors shows promise – for combatting social isolation, increasing well-being and delaying the onset, or slowing the progression, of dementia.
New review finds that over 150 papers strongly support the view that herpes simplex plays a role in Alzheimer’s disease.
With an ageing population, dementia is becoming more and more prevalent. But what does dementia actually do to the brain to cause changes in behaviour?
Media pioneer Ted Turner's announcement that he has Lewy body dementia brings the illness into the spotlight, which is rare. A neurologist explains why it's hard to even get a correct diagnosis.