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Articles on GWAS

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Participants in biobank studies are often asked for broad consent to use their data. Science Photo Library - TEK IMAGE/Brand X Pictures via Getty Images

Researchers can learn a lot with your genetic information, even when you skip survey questions – yesterday’s mode of informed consent doesn’t quite fit today’s biobank studies

Biobanks collect and store large amounts of data that researchers use to conduct a wide range of studies. Making sure participants understand what they’re getting into can help build trust in science.
Statistical pitfalls in GWAS can result in misleading conclusions about whether some traits (like long horns or spotted skin, in the case of dinosaurs) are genetically linked. @meanymoo

People don’t mate randomly – but the flawed assumption that they do is an essential part of many studies linking genes to diseases and traits

People don’t randomly select who they have children with. And that means an underlying assumption in research that tries to link particular genes to certain diseases or traits is wrong.
Ethical and equitable scientific collaboration could help increase the genetic diversity of genomic data. gmast3r/iStock via Getty Images Plus

Uncovering the genetic basis of mental illness requires data and tools that aren’t just based on white people – this international team is collecting DNA samples around the globe

Existing genetic data and sequencing tools are overwhelmingly based on people of European ancestry, which excludes much of the rich genetic variation of the world.
Marius Wernig, Thomas C. Südhof and their colleagues created these “Induced neuronal (iN) cells” from adult human blood cells. Marius Wernig

Neurons made from blood cells – a new tool for understanding brain diseases

Figuring out what causes diseases like autism, schizophrenia and depression is tricky. Now Stanford University researchers are turning blood into brain cells to study these diseases in a dish.

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