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Articles on Human genome

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DNA editing has the capacity to treat many diseases, but how to do this safely and equitably remains unclear. KTSDESIGN/Science Photo Library via Getty Images

Human genome editing offers tantalizing possibilities – but without clear guidelines, many ethical questions still remain

Following the controversial births of the first gene-edited babies, a major focus of the Third International Summit on Human Genome Editing was responsible use of CRISPR.
Statistical pitfalls in GWAS can result in misleading conclusions about whether some traits (like long horns or spotted skin, in the case of dinosaurs) are genetically linked. @meanymoo

People don’t mate randomly – but the flawed assumption that they do is an essential part of many studies linking genes to diseases and traits

People don’t randomly select who they have children with. And that means an underlying assumption in research that tries to link particular genes to certain diseases or traits is wrong.
A complete human genome, seen here in pairs of chromosomes, offers a wealth of information, but it is hard connect genetics to traits or disease. HYanWong/Wikimedia Comons

Scientists are on a path to sequencing 1 million human genomes and use big data to unlock genetic secrets

The first full human genome was sequenced 20 years ago. Now, a project is underway to sequence 1 million genomes to better understand the complex relationship between genetics, diversity and disease.
CRISPR is a gene editing tool that can create permanent changes in the human genome. from www.shutterstock.com

Experts call for halt to CRISPR editing that allows gene changes to pass on to children

Four months ago a researcher claimed he had used the tool CRISPR to edit the genomes of twin girls. Now prominent researchers and ethicists are calling for a temporary halt to this sort of work.
Indigenous Australians must be involved in research around provenance and country. Here, representatives of the Willandra Aboriginal Elders visit the Griffith University ancient DNA laboratory. Renee Chapman

DNA from ancient Aboriginal Australian remains enables their return to Country

Museums around the world hold remains of Aboriginal people that were often taken without permission and in the absence of accurate records. New DNA methods may help return these items to country.

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