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Articles on Microscopy

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This microscopy image shows the retina of a mouse, laid flat and made fluorescent. Kenyoung Kim, Wonkyu Ju and Mark Ellisman/National Center for Microscopy and Imaging Research, University of California, San Diego via Flickr

Seeing what the naked eye can’t − 4 essential reads on how scientists bring the microscopic world into plain sight

Visualization is an essential part of the scientific process. Advances in imaging have enabled eye-opening discoveries, not only for scientists and researchers but also for the general public.
This image of actin filaments in a cell was taken using a type of superresolution microscopy. Xiaowei Zhuang, HHMI, Harvard University, and Nature Publishing Group/NIH via Flickr

Zooming across time and space simultaneously with superresolution to understand how cells divide

Superresolution microscopy allowed researchers to view cells at the molecular level. Improvements on the technique can help study the building blocks of complex cell processes over time.
Imaging the proteins on the surface of HCV has been challenging because of the virus’s shape-shifting nature. Juan Gaertner/Science Photo Library via Getty Images

Scientists uncovered the structure of the key protein for a future hepatitis C vaccine – here’s how they did it

Using a Nobel Prize-winning technique called cryo-EM, researchers were able to identify potential areas on the hepatitis C virus that a vaccine could target.
A nanographene molecule imaged by noncontact atomic force microscopy. Patrik Tschudin/gross3HR/Wikimedia Commons

What do molecules look like?

A physicist explains how atoms arrange themselves into molecules – and how scientists are able to image these tiny bits of matter that make up everything around you.
Eliminating human guesswork can make for faster and more accurate research. KTSDESIGN/Science Photo Library via Getty Images

New AI technique identifies dead cells under the microscope 100 times faster than people can – potentially accelerating research on neurodegenerative diseases like Alzheimer’s

Understanding when and how neurons die is an important part of research on neurodegenerative diseases like Lou Gehrig’s, Alzheimer’s and Parkinson’s diseases.
Research groups supported by the U.S. BRAIN Initiative recently released the most comprehensive map of cell types in the motor cortex of humans, monkeys and mice. Andriy Onufriyenko/Moment via Getty Images

Mapping how the 100 billion cells in the brain all fit together is the brave new world of neuroscience

Scientists have been mapping the brain for centuries. New visualization tools bring them one step closer to understanding where thoughts come from and new ways to treat neurological disorders.
A simple two-dimensional grid can convey a lot of information – whether making pictures with Lite-Brite or storing data in DNA. Justin Day/Flickr

DNA ‘Lite-Brite’ is a promising way to archive data for decades or longer

DNA has been storing vast amounts of biological information for billions of years. Researchers are working to harness DNA for archiving data. A new method uses light to simplify the process.

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