A challenge in eradicating polio comes from a version of the vaccine itself, which relies on live but attenuated virus. Rationally designing a new vaccine could help get rid of polio once and for all.
Polio can be circulating through a community long before anyone is paralyzed. Monitoring sewage for the virus lets public health officials short-circuit this 'silent transmission.'
Pakistan had only eight new diagnoses of polio in 2017. The virus' days look numbered – but health workers have their work cut out for them to eradicate the devastating disease once and for all.