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Articles sur Clinical trials

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More clinical trials in African countries can help ensure that any vaccines or treatments developed cater to the continent’s genetic diversity. CELLOU BINANI/AFP via Getty Images

Few clinical trials are done in Africa: COVID-19 shows why this urgently needs to change

More countries on the African continent must urgently get involved in clinical trials so that the data collected will accurately represent the continent at a genetic level.
Announcement of the Nobel Prize in Economics to Abhijit Banerjee, Esther Duflo and Michael Kremer (from left to right on the screen) during a press conference held at the Royal Swedish Academy of Sciences in Stockholm on 14 October 2019. Jonathan Nackstrand/AFP

2019 Nobel Prize in Economics: the limits of the clinical trial method

The 2019 Nobel Prize in Economics pays tribute to randomized control trials, but can they really help us fight poverty?
Clinical trials are important, but can’t get us to medicine prescribing that is 100% effective. Image Point Fr/Shutterstock.com

Why drug trials are only part of the answer to making sure medicines work

Clinical trials are used to establish that medicines work. But these don't take into account the genetic differences between us that can mean very different outcomes for different patients.
When drug companies and drug regulators, such as Health Canada, sit down together at “pre-submission meetings” this may have a negative impact on public health. (Shutterstock)

Health Canada and Big Pharma: Too close for comfort

Drug companies have a job to do and so does Health Canada. When the relationship becomes murky, the public are at risk.
An MRI image of the brain. SpeedKingz/Shutterstock.com

An unexpected pathway to treating neurodegenerative diseases

Not all drug development needs to start from scratch. Sometimes researchers discover that a drug developed for one disease can be used for another. Here a cancer drug may show promise for dementia.
Research published in Science Translational Medicine in February 2019 used a virtual patient to test the drug, Fevipiprant. (Shutterstock)

A new drug promises to lower risks of asthma attack

Asthma affects around 339 million people worldwide. A new drug promises to lower risks of asthma attack and may eventually allow patients to reduce their dependence on steroids.
Canadian finance minister Bill Morneau announced funding for a new Canadian Drug Agency in the 2019 Federal Budget. Here he speaks at a press conference in Toronto, March 20, 2019. THE CANADIAN PRESS/Cole Burston

Federal budget: A Canadian Drug Agency and rare disease funding are not enough

A new agency and money for drugs for rare diseases are only very partial steps on the road towards what Canada really needs: a national pharmacare plan.
Ear infections are no fun. The OSTRICH clinical trial looked at whether oral steroid medications might help. from www.shutterstock.com

How researchers assess whether medications work

Clinical trials can assess impact of a medication on a disease. The ideal design is 'blind' – when the researchers and participants do not know who is assigned to the different treatments.
Antidepressants bring in almost $17 billion a year for the pharmaceutical industry, and yet science shows their benefit to be small. Natural therapies such as diet, exercise, light therapy and cognitive behavioural therapy are just as effective. (Shutterstock)

Why natural depression therapies are better than pills

These four “natural” therapies for depression have rigorous, peer-reviewed scientific studies to support their use.
Early-onset Alzheimer’s disease presents unique challenges, when a patient is still working or parenting children.The personality changes involved can result in job loss or divorce before a diagnosis is made. (Shutterstock)

Is that ‘midlife crisis’ really Alzheimer’s disease?

Alzheimer's disease affects many people under the age of 65. The 'young-onset' version of the disease is often misdiagnosed as depression or dismissed as a midlife crisis.

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