FTD leads to changes in personality and behavior. Understanding its genetic and molecular causes could lead to new ways to treat neurodegenerative diseases.
Many viruses interact with the olfactory system, and can damage other areas of the brain through it.
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Andrew Bubak, University of Colorado Anschutz Medical Campus; Diego Restrepo, University of Colorado Anschutz Medical Campus et Maria Nagel, University of Colorado Anschutz Medical Campus
Inflammation and damage to the olfactory system from shingles, COVID-19 and herpes infections may contribute to Alzheimer’s disease.
Type 2 diabetes, characterised in its advanced stages by insulin resistance, is an important risk factor for Alzheimer’s disease.
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Impaired insulin receptors in the blood vessels between the blood and the brain may contribute to the insulin resistance observed in Alzheimer’s disease.
Asymptomatic sensitization may lead people to continue consuming food allergens, causing hidden neurological issues.
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Microglia, immune cells disguised as brain cells, are known as the janitors of the brain. Dialing up their usual duties just enough could provide an avenue to treat neurodegenerative disease.
Nonhuman primates like rhesus monkeys share certain characteristics with people that may make them better study subjects than mice for research on neurodegenerative diseases.
The U.S. BRAIN Initiative seeks to elucidate the connection between brain structure and function.
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From figuring out where memories are stored to how sensory information translates to behavior, new technologies are helping neuroscientists better understand how the brain works.
Understanding when and how neurons die is an important part of research on neurodegenerative diseases like Lou Gehrig’s, Alzheimer’s and Parkinson’s diseases.
Our research suggests the multiplication of protein aggregates in individual regions of the brain, rather than their spread between regions, is key to the progression of Alzheimer’s disease.
A plant fruit in Nigeria shows potential for a new drug for epilepsy treatment.
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An extract of a plant’s fruit in Nigeria could protect against seizure and prevent brain degeneration. It could therefore be studied further for the development of a new antiepileptic drug.
Ubiquitin tags in cells serve different functions depending on stress conditions.
Michael Hughes
Brian Andrew Maxwell, St. Jude Children’s Research Hospital Graduate School of Biomedical Sciences
Insight on how a unique protein plays a role in cellular stress responses may provide more clues on how to treat diseases like ALS and Alzheimer’s.
We knew people with Parkinson’s disease were at heightened risk of developing addictive behaviours like gambling. Our research gives insight into why this is.
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Philip Mosley, QIMR Berghofer Medical Research Institute
About one in six people who take the most common medication for Parkinson’s disease will develop addictive behaviours. We found whether this happens depends on a person’s unique brain structure.
An MRI image of the brain.
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Not all drug development needs to start from scratch. Sometimes researchers discover that a drug developed for one disease can be used for another. Here a cancer drug may show promise for dementia.
Figuring out the pieces to the Alzheimer’s puzzle.
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Many pieces leading to Alzheimer’s disease have been identified. To put the pieces together, one scholar argues that the government should launch a Manhattan Project-scale effort to find a cure.
Researchers are developing treatments for blindness caused by neurodegeneration.
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A new type of drug blocks the destruction of neurons in the eye, preventing blindness. The researchers hope that the same therapy can be applied to other common neurodegenerative diseases.