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Opioid neurotransmitters are located in many areas of the body, including the brain, spine and gut. ALIOUI Mohammed Elamine/iStock via Getty Images Plus

Your body naturally produces opioids without causing addiction or overdose – studying how this process works could help reduce the side effects of opioid drugs

Unlike opioid drugs like morphine and fentanyl that travel throughout the body, the opioids your body produces are released in small quantities to specific locations.
One potential way to make opioids less addictive is to make them target injured tissue rather than the healthy brain. PM Images/Photodisk via Getty Images

Designing less addictive opioids, through chemistry

While the COVID-19 pandemic raged on, the opioid epidemic got worse as drug overdose deaths soared. New research proposes a way to chemically modify opioids to reduce the risk of addiction.

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