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Articles sur Clinical trials

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People getting vaccinated may still have questions about COVID-19 vaccines, like why it takes two doses — and then two weeks — to take full effect. THE CANADIAN PRESS/Ryan Remiorz

I work at a COVID-19 vaccine clinic. Here’s what people ask me when they’re getting their shot — and what I tell them

A medical student answers questions he gets asked at a COVID-19 vaccine clinic: Efficacy versus real-world effectiveness, immune response and how the mRNA vaccines compare to vaccines already in wide use.
FDA approval of Pfizer’s COVID-19 vaccine may boost vaccination rates among those who have been hesitant to get the shot. (AP Photo/Jessica Hill)

Pfizer’s COVID-19 vaccine now has full FDA approval. Here’s what that means for unvaccinated people, organizations and pharma

The U.S. FDA has approved the first COVID-19 vaccine. How is approval different from emergency use authorization, and what difference will it make to a vaccine that’s already in global use?
Vaccine efficacy statistics are often based on the results of randomized controlled trials. (Art-Aleatoire.com)

How effective are COVID-19 vaccines? Here’s what the stats mean … and what they don’t

Vaccine efficacy is usually expressed as a percentage, but what is it actually measuring? Statisticians explain what the numbers mean, and what they say about how well a vaccine can protect us.
Crystal jellyfish contain glowing proteins that scientists repurpose for an endless array of studies. Weili Li/Moment via Getty Images

From CRISPR to glowing proteins to optogenetics – scientists’ most powerful technologies have been borrowed from nature

Three pioneering technologies have forever altered how researchers do their work and promise to revolutionize medicine, from correcting genetic disorders to treating degenerative brain diseases.
Information on COVID-19 vaccines for pregnant or breastfeeding individuals has been inconsistent and hard to find. (AP Photo/Charles Krupa)

Should I get the COVID-19 vaccine while pregnant or breastfeeding? Experts explain the safety, evidence and clinical trials

Exclusion from clinical trials, lack of data and inconsistent information made it difficult for pregnant and breastfeeding people to make decisions about COVID-19 vaccines early in the rollout.
Alzheimer’s disease is characterized by progressive memory loss, spatial disorientation and many other cognitive and behavioural disorders that ultimately lead to a state of total dependence. (Shutterstock)

FDA approval of controversial Alzheimer’s drug could delay discovery of more promising treatments

The new drug is based on the idea that a build-up of amyloid in the brain leads to the disease. But that hypothesis has been under scrutiny lately.
Do the benefits of approving a drug before confirming it works outweigh the potential costs? monkeybusinessimages/iStock via Getty Images Plus

The FDA’s big gamble on the new Alzheimer’s drug

The FDA approved Alzheimer’s disease drug aducanumab despite minimal evidence of its efficacy. Whether this decision ultimately hurts or helps patients depends on data researchers don’t yet have.
A COVID-19 vaccine is administered at a clinic at Olympic Stadium in Montréal on March 1, 2021, marking the beginning of mass vaccination in the Province of Québec based on age. THE CANADIAN PRESS/Paul Chiasson

COVID-19 vaccine FAQs: Efficacy, immunity to illness vs. infection (yes, they’re different), new variants and the likelihood of eradication

With four COVID-19 vaccines approved for use in Canada, it’s time to answer FAQs about efficacy, immunity, eradication and variants.

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