UWA researchers have identified a number of genes that increase the risk of Paget’s disease, a chronic and painful bone condition that causes inflammation and deformity in one in 20 people over the age of 55.
A large part of the genetic risk of Paget’s disease in individuals is accounted for by these genes, some of which are known to play important roles in bone metabolism, while others have not previously been linked to bone regulation.
These genes are likely to be important in bone health, and may play a part in other bone diseases such as osteoporosis and bone cancer.
Read more at The University of Western Australia