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A mural in Rome depicts a white dove parachuting vials of COVID-19 vaccine. Several COVID-19 vaccines are based on a viral vector developed by Canadian Frank Graham decades ago. (AP Photo/Gregorio Borgia)

How the puzzle of viral vector vaccines was solved, leading to today’s COVID-19 shots

Viral vectors are modified viruses that trigger an immune response without causing infection. The vector that’s used in several COVID-19 vaccines was created decades ago by Canadian Frank Graham.
There are many ways to make a vaccine. In a time of crisis, the more paths towards success the better. Adriana Duduleanu / EyeEm via Getty Images

Labs are experimenting with new – but unproven – methods to create a coronavirus vaccine fast

Under pressure to develop a coronavirus vaccine, researchers have turned to protein synthesis, genetics and hybrid viruses. It is likely a mix of these approaches will be used to fight the coronavirus.

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