A cancer that spreads is much more dangerous. Here’s why – and how it happens.
Academic rigor, journalistic flair
Walter and Eliza Hall Institute
The Walter and Eliza Hall Institute is Australia’s oldest medical research institute, founded in 1915.
The Institute has more than 850 researchers who are working to understand, prevent and treat diseases including: cancers such as breast, blood and bowel cancers; immune disorders such as diabetes, coeliac disease and multiple sclerosis; and infectious diseases including malaria, hepatitis B and HIV.
Our affiliation with The Royal Melbourne Hospital links research outcomes with clinical practice to accelerate discoveries for health and disease. We offer postgraduate training as the Department of Medical Biology of The University of Melbourne.
More than 30 million people worldwide have been helped by discoveries made at the Institute and more than 100 national and international clinical trials are underway that originate from Institute research. This include trials of vaccines and therapies for type 1 diabetes, coeliac disease and malaria; trials of new anti-inflammatory agents for arthritis and other immune disorders; and trials of a new class of anti-cancer drugs, called BH3-mimetics, for treating patients with leukaemia and other cancers.
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Lots of people report bruising easily. What do doctors look for to see if it might be caused by something serious?
Studi kami pada tikus menunjukkan perubahan epigenetik pada ibu dapat diturunkan ke keturunannya untuk mempengaruhi waktu kritis dalam bagaimana tulang belakang berkembang.
Our study in mice shows epigenetic changes in the mother can be passed to her offspring to influence a critical time in how the spine develops.
Tracking mosquitoes is essential to understanding their pest and public health risks. You can help too – here’s how.
Australian scientists are no more honest or dishonest than those in other countries that have national bodies to investigate research fraud. We have a sport integrity watchdog but not one for research.
If you have risk factors around blood clots, heart attack or stroke, this should actually be an impetus to get vaccinated sooner rather than later.
While we don’t know exactly what causes it yet, there are a few leading theories put forward by researchers around the world.
For people who are immunodeficient, the usual controls of the immune system don’t work as well. This can affect how they respond to vaccines. But this group should still get the COVID jab.
Australia’s keenly awaited COVID vaccine rollout begins today. So how will it work, and will the vaccine be the end of all our coronavirus-related problems?
Children in the study seemed to display a very strong “innate” immune response.
It may not be long before Australia’s health sector offers predictive genomic analysis to patients. If this happens, could chatbots help lessen the load on genetic counsellors?
If the coronavirus is a lock, a drug to defeat it is a key that needs to fit just right.
A rare type of inflammatory disease that causes repeated bouts of high temperatures can run in families. Here’s what we know so far.
The cornerstone of our adaptive immune system is the ability to remember the various infections we have encountered. Quite literally, if it doesn’t kill you, it makes your immune system stronger.
Today, human populations carry heavy genetic marks from the war with malaria. And it is the red blood cell (erythrocyte) that mostly bears the scars.
We have no reliable way of knowing which patients’ cancer will return after surgery, so often chemotherapy is given to mop up any remaining cancer cells that may have gone undetected.
As we age, our DNA accumulates damage, which can increase our risk of developing
cancer. But our cells work hard to guard against cancer – new research explains how.
Without a national office for research integrity, Australia risks losing scientists and research funders to countries with more robust setups.
Immunotherapy drugs work by increasing the patient’s own immune response. The most successful examples of immunotherapies are drugs that act as antibodies, of which Keytruda is one.
Authors
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Laboratory Head, Immunology Division, Walter and Eliza Hall Institute
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Executive Director, Melbourne Genomics Health Alliance, Walter and Eliza Hall Institute
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Medical Researcher, Walter and Eliza Hall Institute
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Head, Chemical Biology Division, Walter and Eliza Hall Institute
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Laboratory Head, Walter and Eliza Hall Institute
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Senior Resarch Officer, Walter and Eliza Hall Institute
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Researcher, Walter and Eliza Hall Institute
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Masters of Research Student, Walter and Eliza Hall Institute
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Head, Molecular Medicine Laboratory, Walter and Eliza Hall Institute
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Postdoctoral Research Fellow, Walter and Eliza Hall Institute
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PhD Student, Epigenetics and Development Division, Walter and Eliza Hall Institute
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Senior Postdoctoral Research Fellow, Walter and Eliza Hall Institute
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Division Head, Population Health and Immunity, Walter and Eliza Hall Institute
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Senior Research Officer, Blood Cells and Blood Cancer Division, Walter and Eliza Hall Institute
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Laboratory Head, Immunology Division, Walter and Eliza Hall Institute
