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Keeping cancer cells alive

A new study has demonstrated how we can alter the survival of cancer cells.

The work demonstrates for the first time that the active sarcoma (Src) gene product is differentially targeted in cancer cells to maintain their viability.

Research reagents prepared by Professor Wally Langdon from the UWA School of Pathology and Laboratory Medicine were used to help determine the mechanism by which another cancer-causing protein called Cbl contributes to this process. Cbl was found to sequester active Src and direct its trafficking and degradation by a process known as autophagy.

Read more at The University of Western Australia

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