PET scans using a special tracer can pick up ‘tau tangles’ in the brain.
Vocabulary surrounding Alzheimer’s and other related disorders must be carefully chosen. Here, sculpture by Jaume Plensa, in Montréal.
Arts-related activities for people living with Alzheimer’s and other related disorders could improve people’s quality of life, but collaborating in communities requires a common language.
The author and a trial participant using Fastball.
University of Bath
New diagnostic tool for dementia could improve early detection.
People wearing masks while having oxygen therapy in hyperbaric chamber.
Hyperbaric oxygen therapy helped to reduce plaques in the brains of mice with Alzheimer’s disease.
A runner wears a respirator on a smoky day in Portland, Oregon, in 2020.
Robyn Beck/AFP via Getty Images
To stay healthy, it’s important to understand how wildfire smoke can harm your body and how to protect yourself.
Aducanumab (Aduhelm) was approved in the U.S., but there is no convincing evidence the drug will help Alzheimer’s patients.
FDA approval of aducanumab (Aduhelm) was contentious. Its submission to Health Canada for approval highlights concerns about evidence, independence and transparency in Canada’s drug approval process.
There are different types of memory and not all of them are related to Alzheimer’s disease.
Alzheimer’s disease is often associated with a decline in episodic memory. Patients will complain that they can’t remember events they’ve experienced, conversations they’ve had, things they’ve done.
Alzheimer’s, like many diseases, has a genetic component.
Tek Images/Science Photo Library via Getty Images
Using a technique called admixture mapping, researchers can leverage the diversity of people with mixed ancestry to look for hard-to-find genetic risk factors for diseases like Alzheimer’s disease.
Ubiquitin tags in cells serve different functions depending on stress conditions.
Insight on how a unique protein plays a role in cellular stress responses may provide more clues on how to treat diseases like ALS and Alzheimer’s.
Clinical trials of the drug have shown mixed results.
Alzheimer’s disease is characterized by progressive memory loss, spatial disorientation and many other cognitive and behavioural disorders that ultimately lead to a state of total dependence.
The new drug is based on the idea that a build-up of amyloid in the brain leads to the disease. But that hypothesis has been under scrutiny lately.
More research is needed to prove the drug slows cognitive decline.
Atthapon Raksthaput/ Shutterstock
The first drug targeting Alzheimer’s disease has been approved in 20 years – but its approval isn’t based on substantial evidence.
Do the benefits of approving a drug before confirming it works outweigh the potential costs?
monkeybusinessimages/iStock via Getty Images Plus
The FDA approved Alzheimer’s disease drug aducanumab despite minimal evidence of its efficacy. Whether this decision ultimately hurts or helps patients depends on data researchers don’t yet have.
Isolation and segregation create and reinforce another kind of barrier to those with dementia: stigma.
‘Dementia friendly’ communities seek to support people with memory loss, recognize them as equals, celebrate their contributions and enable them to live with purpose in welcoming communities.
The colors in this microscope photo of a fruit fly brain show different types of neurons and the cells that surround them in the brain.
Sarah DeGenova Ackerman
Adaptable neurons are tied to learning and memory but also to neurological disorders. By studying fruit flies, researchers found a mechanism that controls neuroplasticity.
Olivia Coleman and Anthony Hopkins in The Father (2020)
A neuroscientist and a clinician watched two new films about dementia. They recognised what they saw.
The equivalent of one bacon rasher was associated with 44% increased dementia risk.
If so, it’s just one lifestyle risk among many others.
Nanodiamonds aren’t just cellular bling: they could be used to better understand the development of cancer in our cells.
Currently, the only approved drugs for Alzheimer’s merely alleviate some of the symptoms — partially and temporarily — but do not stop the disease from progressing.
It was first officially described 115 years ago, but we still do not have a cure for Alzheimer’s disease. The human brain is extremely complex, and Alzheimer’s is its most complex disease.
The final piece in the dementia puzzle is at the door.