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Articles on Clinical trials

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On Aug. 11, Russian President Vladimir Putin announced that a coronavirus vaccine developed in the country has been registered for use. Russian Health Ministry/Handout/Anadolu Agency via Getty Images

A COVID-19 vaccine needs the public’s trust – and it’s risky to cut corners on clinical trials, as Russia is

As Russia fast tracks a coronavirus vaccine, scientists worry about skipped safety checks – and the potential fallout for trust in vaccines if something ends up going wrong.
A man with ALS uses a head-mounted laser pointer to communicate with his wife, by pointing to letters and words on a communication board. Fezcat via Wikipedia.com

ALS scientific breakthrough: Diabetes drug metformin shows promise in mouse study for a common type of ALS

Amyotrophic lateral sclerosis, Lou Gehrig’s disease, is a crippling, progressive neurodegenerative disease for which there is no cure. Now it seems that a diabetes drug may help some cases.
Vaccinologists have not focused their research on tailoring vaccines to induce robust immune responses in the elderly. (Shutterstock)

Why vaccines are less effective in the elderly, and what it means for COVID-19

Immunosenescence — the decline of immune system function with age — means that vaccines are not as effective in older adults, the demographic most susceptible to many diseases, including COVID-19.
Loneliness affects one in three people in the industrialized world, with racialized groups disproportionately bearing the burden. (Pexels/EricW)

Cancer and loneliness: How inclusion could save lives

Pluralism — the active process of inclusion — could reduce disparities in some of the most pressing health issues of our time.
A volunteer receives an injection from a medical worker during the country’s first human clinical trial for a potential vaccine against COVID-19 in Soweto, South Africa. Felix Dlangamandla/Beeld/Gallo Images via Getty Images

COVID-19 vaccine: the challenges of running a trial in the middle of a pandemic

In a pandemic like this one, the priority is to save lives. But without a vaccine, there’s a limit in the tools available to save lives.
Breathing in through the nose is an integral part of meditation and delivers virus-fighting gases to the lungs. triloks / Getty Images

The right way to breathe during the coronavirus pandemic

The body has many natural defenses against viruses and other pathogens. One antiviral molecule produced in the body is nitric oxide and it is created when we breathe in through the nose.
The scope and length of vaccine testing experiments usually mean decade-long timelines for development. (Pixabay)

Fast COVID-19 vaccine timelines are unrealistic and put the integrity of scientists at risk

It usually takes 10 years for a new vaccine to complete clinical trials, but we’ve been promised a COVID-19 vaccine in 12 to 18 months. Even if such fast-tracked development is possible, is it wise?
Laboratories around the world are working round the clock to find treatments or a vaccine for COVID-19. Getty Images / Kena Betancur

Could pressure for COVID-19 drugs lead the FDA to lower its standards?

The FDA has sped up its approval process for coronavirus treatments, creating a new division to expedite the regulatory process. But is safety being sidelined for speed?

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