Alastair is a Reader at the Preventive Neurology Unit at the Wolfson Institute of Preventive Medicine, Queen Mary University of London, and a Consultant Neurologist for Barts Health NHS Trust. His main research interests are Parkinson’s disease and related neurodegenerative disorders, particularly early identification and epidemiology, including environmental, clinical and genetic determinants. His other interests include objective measurement of motor and non-motor features of Parkinson’s.
Over the last 9 years he has led the PREDICT-PD study, which is a large cohort study that aims to identify those in the earliest stages of Parkinson’s, who may one day benefit from drugs that could slow or even halt the disease. Alongside PREDICT-PD he works on a variety of other observational studies, in the phases of Parkinson’s disease both pre-diagnosis and post-diagnosis. He has nurtured an interest in genetic epidemiology and the use of common genetic variation to estimate the nature of causal relationships between a variety of risk factors and Parkinson’s (so-called Mendelian randomisation).