Mhajne is a political scientist specializing in international relations and comparative politics with a focus on gender and politics. Her current research is at the intersection of gender, religion, and Middle Eastern politics. Mhajne focuses on how Islamic beliefs and institutions in the Middle East structure Muslim women’s political understandings, agencies, and opportunities at local, national and international levels. Due to her political science and interdisciplinary training in gender politics, international relations, and comparative politics, Mhajne's research strengths lie in the following areas: Feminist International Relations and Security Studies; Democratization; Governance and Institutions; Civil Society and Activism; Political Islam; Middle East; Gender Politics; Social Movements; and Regime Change. Mhajne's work has been featured in The International Feminist Journal of Politics, The Conversation, Middle East Eye, and Carnegie Endowment for International Peace.