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Wellcome Trust Research Fellow, Institute of Cancer Research, London

Dr Chris Bakal studies the biological switches that cause cells to change shape, become cancerous and spread around the body. By understanding how these switches work, scientists may one day find a way to control them through drugs or other therapies. Dr Bakal is Leader of the Dynamical Cell Systems Team within the Division of Cancer Biology at the The Institute of Cancer Research.

Cells are able to assume a wide variety of complex shapes in order to carry out different roles and Dr Bakal’s team examines the genetic and biochemical mechanisms that underpin these shape changes. Their research covers how both environmental and genetic variation affects cell shape. Ultimately, Dr Bakal aims to understand how normal and cancerous cells can adopt different shapes and why metastatic cancer develops in some people but not others