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Dr John Muthii Muriuki

Dr John Muriuki is a medical scientist working on the complex interaction between infection and nutritional deficiencies. He has extensive experience applying both epidemiological and genetic approaches in his research work. He holds a PhD from Open University (UK).

Selected publications:

1. John Muthii Muriuki, Alexander J Mentzer, Ruth Mitchell, Emily L Webb, Anthony O. Etyang, Catherine Kyobutungi, Alireza Morovat, Wandia Kimita, Francis M Ndungu, Alex W Macharia, et al. (2021) “Malaria is a cause of iron deficiency in African children” Nature Medicine 7:653- 658. DOI: 10.1038/s41591-021-01238-4. PMCID: PMC7610676.

2. Kelvin M. Abuga, John Muthii Muriuki, Sophie M. Uyoga, Kennedy Mwai, Johnstone Makale, Reagan Mogire, Alex W. Macharia, Shebe Mohammed, Salim Mwarumba, Neema Mturi et al (2021). “Hepcidin regulation in Kenyan children with severe malaria and non-typhoidal Salmonella bacteremia.” Haematologica. DOI: 10.3324/haematol.2021.279316. PMID: 34498446.

3. Reagan M. Mogire, Alireza Morovat, John Muthii Muriuki, Alexander J. Mentzer, Emily L. Webb, Wandia Kimita, Francis M. Ndungu, Alex W. Macharia, Clare L. Cutland, Sodiomon B. Sirima et al (2021). Prevalence and predictors of vitamin D deficiency in young African children. BMC Medicine. 19:115. DOI: 10.1186/s12916-021-01985-8. PMCID: PMC8136043.

4. John Muthii Muriuki, Alexander J Mentzer, Emily L Webb, Alireza Morovat, Wandia Kimita, Francis M Ndungu, Alex W Macharia, Rosie J. Crane, James A. Berkley, Swaib A. Lule, et al. (2020) “Estimating the burden of iron deficiency in African children” BMC Medicine. 18:31. DOI: 10.1186/s12916-020-1502-7. PMCID: PMC7045745.

5. Kelvin M. Abuga, Kirk A. Rockett, John Muthii Muriuki, Oliver Koch, Manfred Nairz, Giorgio Sirugo, Philip Bejon, Dominic P. Kwiatkowski, Andrew M. Prentice, Sarah H. Atkinson. (2020) “Interferon-gamma polymorphisms and risk of iron deficiency and anaemia in Gambian children” Wellcome Open Research 5:40. DOI: 10.12688/wellcomeopenres.15750.2. PMCID: PMC7202087.

6. Caroline K Bundi, Angela Nalwoga, Lawrence Lubyayi, John Muthii Muriuki, Reagan M Mogire, Herbert Opi, Alexander J Mentzer, Cleopatra K Mugyenyi, Jedida Mwacharo, Emily L Webb, et al (2020). "Iron deficiency is associated with reduced levels of Plasmodium falciparum-specific antibodies in African children" Clinical Infectious Diseases. ciaa728. DOI: 10.1093/cid/ciaa728. PMID: 32507899.

7. Kelvin M Abuga, John Muthii Muriuki, Thomas N Williams, Sarah H Atkinson. (2020). “How Severe Anaemia Might Influence the Risk of Invasive Bacterial Infections in African Children” International Journal of Molecular Sciences 21:6976. DOI: 10.3390/ijms21186976. PMCID: PMC7555399.

8. Daniel Wright, Elizabeth Allen, Madeleine H.A. Clark, John N. Gitonga, Henry K. Karanja, Ruben Hulswit, Iona Taylor, Sumi Biswas, Jennifer Marwill, Damaris Mwololo, John Muriuki, et al (2020). Naturally acquired Rift Valley fever virus neutralizing antibodies predominantly target the Gn glycoprotein. iScience. 23:101669. DOI: 10.1016/j.isci.2020.101669

9. Arithi Mutembei, Festus K. Mutai, Damaris Mwololo, John Muriuki, Mark Obonyo, S.W. Kairu- Wanyoike, M. Wainaina, J. Lindahl, E. Ontiri, S. Bukachi, et al (2020). Leptospira spp. seroprevalence in humans involved in a cross-sectional study in Garissa and Tana River Counties, Kenya. Preprint

10. John Muthii Muriuki, Alexander J Mentzer, Gavin Band, James Gilchrist, Tommy Carstensen, Swaib Lule, Morgan Goheen, Fatou Joof, Wandia Kimita, Reagan Mogire, et al. (2019). “The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia” Science Advances 5 (9): eaaw0109. DOI: 10.1126/sciadv.aaw0109. PMCID: PMC6726445.

11. John Muthii Muriuki, Alexander J Mentzer, Wandia Kimita, Francis M Ndungu, Alex W Macharia, Emily L Webb, Swaib A Lule, Alireza Morovat, Adrian V. S. Hill, Philip Bejon, et al. (2019). “Iron Status and Associated Malaria Risk Among African Children” Clinical Infectious Diseases 68 (11): 1807-1814. DOI: 10.1093/cid/ciy791. PMCID: PMC6522755.

12. John Muthii Muriuki, and Sarah Atkinson. (2018). “How Eliminating Malaria May Also Prevent Iron Deficiency in African Children” Pharmaceuticals 11 (4): 96. DOI: 10.3390/ph11040096. PMCID: PMC6315967.

13. John Muthii Muriuki, Philip Kitala, Gerald Muchemi, Ian Njeru, Joan Karanja, and Bernard Bett. (2016). “A Comparison of Malaria Prevalence, Control and Management Strategies in Irrigated and Non-Irrigated Areas in Eastern Kenya” Malaria Journal 15 (1): 402. DOI: 10.1186/s12936-016-1458- 4.

14. Mogire RM, Muriuki John Muthii, Morovat A, Mentzer AJ, Webb EL, Kimita W, Ndungu FM, Macharia AW, Cutland CL, Sirima SB, Diarra A, Tiono AB, Lule SA, Madhi SA, Prentice AM, Bejon P, Pettifor JM, Elliott AM, Adeyemo A, Williams TN, Atkinson SH. “Vitamin D Deficiency and Its Association with Iron Deficiency in African Children” Nutrients. 2022 Mar 25;14(7):1372. doi: 10.3390/nu14071372.PMID: 35405984.

15. Nampijja M, Mutua AM, Elliott AM, Muriuki John Muthii, Abubakar A, Webb EL, Atkinson SH. “Low Hemoglobin Levels Are Associated with Reduced Psychomotor and Language Abilities in Young Ugandan Children.” Nutrients. 2022 Mar 30;14(7):1452. doi: 10.3390/nu14071452. PMID: 35406065.