Fulvio D'Acquisto

Professor of Immunopharmacology, Queen Mary University of London

Fulvio D’Acquisto graduated in Pharmaceutical Chemistry in 1993 from the University of Naples “Federico II” and trained in Pharmacology at the Department of Experimental Pharmacology of the Faculty of Pharmacy. In 1996 he obtained the Master in Experimental Pharmacology working on mechanisms by which Annexin-A1 controls gene expression in inflammation.

During his PhD in Experimental Pharmacology (1996 to 1999) he studied the role of the transcription factor NF-kB in different models of acute and chronic inflammation demonstrating that inhibitors of NF-kB activation display a remarkable in vivo anti-inflammatory activity. He directed his efforts on this research path even further after beginning his post-doctoral training in the laboratory of Prof. Sankar Ghosh, at Yale University (1999), where he investigated novel approaches to successfully target the NF-?B pathway and that can be used as anti-inflammatory therapy. During this time (from 1999-2003) he expanded his knowledge on inflammation by focusing on immune-mediated inflammatory diseases and investigated signalling pathways by which the T cell receptor activates NF-?B in T cells.

Since July 2003, he joined Prof. Perretti and Prof Flower’s lab at WHRI where he re-activated his long-term interest in Annexin-A1 biology, starting an unexplored path in the role of this protein in the adaptive immune response. In December 2004 he was awarded the New Investigator Award of the Medical Research Council. In 2006 he was appointed as Senior Lecturer in Immunopharmacology within the Centre for Biochemical Pharmacology at WHRI. In 2009 he was conferred the title of Reader in Immunopharmacology. In 2014 he was nominated Deputy Director of the Centre for Biochemical Pharmacology and Biomedical Research Theme Lead for the Life Science Institute

Experience

  • –present
    Professor, Queen Mary University of London

Publications

  • 2016
    Editorial overview: Immunomodulation: Exploiting the circle between emotions and immunity: impact on pharmacological treatments., Curr Opin Pharmacol.
  • 2015
    Impaired sense of smell and altered olfactory system in RAG-1(-∕-) immunodeficient mice., Front Neurosci
  • 2015
    Massage-like stroking boosts the immune system in mice., Sci Rep
  • 2014
    Smile--It's in your blood!, Biochem Pharmacol.
  • 2014
    Formyl peptide receptor as a novel therapeutic target for anxiety-related disorders., PLoS One.
  • 2014
    'As above, so below' examining the interplay between emotion and the immune system., Immunology.
  • 2013
    Emotional change-associated T cell mobilization at the early stage of a mouse model of multiple sclerosis., Front Immunol.
  • 2013
    CD4⁺ but not CD8⁺ T cells revert the impaired emotional behavior of immunocompromised RAG-1-deficient mice., Transl Psychiatry.