Research Associate (Institute of Cancer Sciences), University of Glasgow

Senior computational biologist working on the analysis, visualisation and interpretation of multi-omic leukaemia data using systems biology methodologies. Athena SWAN self-assessment team member and STEM ambassador.

Experience

  • 2010–present
    Research Associate (Institute of Cancer Sciences), University of Glasgow
  • 2009–2010
    Research Assistant (Department of Computing Science), University of Glasgow

Education

  • 2009 
    University College London, PhD Bioinformatics
  • 2005 
    University of Glasgow, MRes Bioinformatics
  • 2004 
    University of Edinburgh, BSc AI and Psychology

Publications

  • 2017
    CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression., Blood
  • 2016
    Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor treated CML stem cells., Blood
  • 2016
    Epigenetic reprogramming sensitizes CML stem cells to combined EZH2 and tyrosine kinase inhibition., Cancer Discovery
  • 2016
    Dual targeting of P53 and C-MYC induces selective elimination of leukemic stem cells., Nature

Grants and Contracts

  • 2016
    Single cell RNA sequencing on primative human leukaemic stem cell population to identify novel biomarkers involved in drug resistance and future immunotherapy
    Role:
    Co-applicant
    Funding Source:
    ISSF Wellcome Trust
  • 2016
    Exploring gene expression in individual CML stem cells to predict response to therapy in newly diagnosed patients
    Role:
    Lead applicant
    Funding Source:
    Tenovus Scotland