Louise Mackenzie

I am a senior lecturer in Pharmacology at the University of Hertfordshire, with a research background in vascular and respiratory pharmacology. I completed my PhD in 2003 at the NHLI, Imperial College (St Mary’s Hospital) in medical biochemistry, working on human vascular smooth muscle cell signalling pathways. For the following 10 years I worked as a post-doctoral researcher at the NHLI (Imperial College) and the William Harvey Research Institute (Queen Mary’s University) with Prof Jane Mitchell and Prof Tim Warner.
My current research areas are eicosanoid and PPAR biology in cardiovascular and respiratory pharmacology, with specific interests in how small changes in vascular hormones lead to long term changes in health. Research expertise extends into resistance vessel bioassay in vitro with particular reference to the role and modulation of nitric oxide, eicosanoids, cyclooxygenase (COX) enzymes, and PPARβ/δ receptors on organ function. More recently I have been asked to help on new projects, including screening novel compounds to control pancreatic cancer and diabetes