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Associate Professor of Biochemistry, University of Oxford

My lab studies the molecular and cellular basis of ageing to identify specific biochemical processes and pathways that change as cells and organisms age. We are particularly interested in cellular senescence, a process which may underpin serious age-related diseases including arthritis, cardiovascular disease, lung fibrosis, neurodegeneration, retinopathy and some cancers. By combining traditional target-based studies with broader phenotypic and systems biology approaches, we can identify new ways to control the damaging aspects of cell senescence, with the aim of discovering novel drugs (and their targets) to treat or even prevent multiple diseases associated with later life.


  • –present
    Associate Professor of Ageing, University of Oxford