Nick trained as a medical doctor and subsequently specialised as a public health physician. He has over 450 Medline-indexed publications in peer-reviewed journals. His research interests include:
- The health economics of primary prevention (see the BODE³ Programme).
- Tobacco use epidemiology and control (see the ITC project website and other tobacco control work).
- Infectious disease control (particularly pandemic influenza but also other infectious diseases).
- Climate change and air pollution.