I am a Senior Lecturer in Cell Biology in the University of Central Lancashire, Preston, UK. I lead an research lab focused on understanding the causes of neurodegenerative disorders, including Alzheimer's disease and motor neurone disease.
We have particular interests around the way in which the non-neuronal cells of the nervous system - the glia - change in these conditions. We think that these cells might make neurodegeneration worse and hope that by understanding how this happens we can identify new targets for treatment.
My lab utilises models ranging from to human induced pluripotent stem cell-derived glia to primary human brain cells and exploit strong links with Royal Preston Hospital and the NIHR Lancashire Clinical Research Facility to examine patient samples.
Side projects include the identification of biomarkers in the blood which can be used to help clinicians diagnose neuropathologies, like motor neurone disease and glioma patient.