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Articles on Drug repurposing
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Cardiovascular disease and cancer share many parallels in their origins and how they develop. Nanoparticles offer one potential way to effectively treat both with reduced side effects.
Despite technological advancements, many challenges remain in getting a drug from lab to pharmacy shelf. Reframing what is a “medicine” could expand treatment options for researchers and patients.
One of the oldest and deadliest diseases, malaria caused more than 627,000 deaths in 2020. A new treatment based on a drug initially developed to fight cancer has shown considerable promise.
Drug repurposing can redeem failed treatments and squeeze out new uses from others. But many pharmaceutical companies are hesitant to retool existing drugs without a high return on investment.
Ivermectin has been a lifesaving drug for people with parasitic infections like river blindness and strongyloidiasis. But taking it for COVID-19 may result in the opposite effect.
Top contributors
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Associate Professor of Pharmacy, University of Connecticut
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Assistant Professor of History, University at Buffalo
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Assistant Professor of Internal Medicine and Medicinal Chemistry, University of Michigan
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Director of Natural Product Discovery Core; Assistant Professor of Medicinal Chemistry, University of Michigan
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Professor of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus
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Assistant Professor of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus
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Research director in parasitology, Inserm
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Associate Professor of Biomedical Engineering, Michigan State University
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Professor in Clinical Pharmacy, Aston University
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Senior lecturer in Pharmacoepidemiology, Aston University
