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Articles on Biomedical research

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The lung-on-a-chip can mimic both the physical and mechanical qualities of a human lung. Wyss Institute for Biologically Inspired Engineering, Harvard University/Flickr

Organ-on-a-chip models allow researchers to conduct studies closer to real-life conditions – and possibly grease the drug development pipeline

Successes in the lab mostly don’t translate to people. Research models that better mimic the human body could close the gap.
Nanoparticles (white disks) can be used to deliver treatment to cells (blue). Brenda Melendez and Rita Serda/National Cancer Institute, National Institutes of Health

Nanomedicines for various diseases are in development – but research facilities produce vastly inconsistent results on how the body will react to them

The proteins that cover nanoparticles are essential to understanding how they work in the body. Across 17 proteomics facilities in the US, less than 2% of the identified proteins were identical.
It can be painful for researchers to read harshly worded criticism of their work from peer reviewers. (Shutterstock)

Peer review: Can this critical step in the publication of science research be kinder?

Peer review of research sounds like it should be a conversation between equals. Instead, it can be patronizing, demanding and simply unkind. A group of journal editors thinks this should change.
Preclinical research — the kind that takes place before testing on humans — often guides decisions about which potential treatments should continue to clinical trials. But attempts to replicate 50 studies found the odds of getting the same results were only about 50-50. (Pexels/Artem Podrez)

Major study shows the need to improve how scientists approach early-stage cancer research

Preclinical studies are an important part of biomedical research, often guiding future trials in humans. Failure to replicate research results suggests a need to increase the quality of studies.
People wearing masks walk in front of Pfizer’s headquarters in New York City. Pfizer and BioNtech are on track with a vaccine that is 90 per cent effective, say preliminary results, but they are not the only ones in the race. AP Photo/Bebeto Matthews

COVID-19 vaccine update: Pfizer may be the frontrunner, but Canada has hedged its bets

Canada has set aside a total of 414 million doses of different types of vaccine. Some exploit known mechanisms, others are based on previously untested approaches.
Artificial intelligence can do what humans can’t – connect the dots across the majority of coronavirus research. baranozdemir/E+ via Getty Images

AI tool searches thousands of scientific papers to guide researchers to coronavirus insights

The scientific community is churning out vast quantities of research about the coronavirus pandemic – far too much for researchers to absorb. An AI system aims to do the heavy lifting for them.

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