Family history may be the most important thing to take into account when it comes to breast cancer risk.
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Articles on BRCA2
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Men with faults in their BRCA2 gene are at higher risk of aggressive prostate cancer.
Alex Trebek announced this week that his pancreatic cancer is in remission. A pancreatic cancer specialist explains the difficulties of the disease as well as new treatment advances.
Individuals who carry the breast cancer genes BRCA1 or BRCA2 are often unaware of the fact. That suggests that physicians need a new way to apply DNA-based screens to identify those at risk.
Mutations in BRCA genes are linked to the early onset of breast and ovarian cancers. But the effect of most mutations is unclear. Now new research can distinguish harmless from dangerous mutations.
We now have the capacity to quickly and cheaply sequence an individual’s genome and scour it for disease-causing genes. But how much, and what type, of information does a parent-to-be want to know?
A genetics testing company recently won approval from the FDA to market a test that can identify a breast cancer gene mutation. But what are women supposed to do with that information? There’s risk involved.
The recipients of this year’s Nobel Prize for Chemistry showed that DNA is far from static. Rather, it is bombarded by damaging forces, but our bodies know how to repair these precious strands.
What if you could take a simple test to reveal your individual risk of developing a range of cancers and hundreds of other diseases?
The High Court challenge is the last resort for Ms D'Arcy’s test case against companies patenting human genes and has implications for patients, clinicians and researchers.
It is well established that faults in the BRCA2 gene (and the BRCA1 gene that prompted actress Angelina Jolie to undergo a mastectomy) increase the risk of breast, ovarian, prostate and other cancers…
The Federal Court’s decision that gene patenting is permitted in Australia will have ramifications for all gene patents, even though the case involved only one gene associated with breast cancer. A gene…
A Federal Court decision to allow gene patents could open the way for existing patents to be enforced more strongly in Australia, according to an expert in intellectual property. Biotechnology companies…
Women with the BRCA1 mutation should have their ovaries removed before the age of 35 to reduce their risk of ovarian and…
Use of the anti-cancer drug Tamoxifen is associated with a dramatically reduced risk of developing a second breast tumour among women with a high risk gene mutation who have experienced breast cancer already…
All nine members of the US Supreme Court have ruled that isolated genetic material cannot be patented – unless the material is markedly different to what exists in nature. The court ruled against Myriad…
Following Hollywood actress Angelina Jolie’s revelation last week that she’d undergone a double mastectomy to prevent breast cancer, it has emerged that a 53-year-old man had his prostate removed after…
Angelina Jolie’s recent announcement about her double mastectomy likely caused many women to think about their own chance of developing breast cancer. But before you rush off to have a bunch of possibly…
Top contributors
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Adjunct Professor, Murdoch University
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Executive Director, Melbourne Genomics Health Alliance, WEHI (Walter and Eliza Hall Institute of Medical Research)
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QIMR Berghofer Medical Research Institute
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Medical Oncologist and Laboratory Head, WEHI (Walter and Eliza Hall Institute of Medical Research)
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Adjunct Professsor, School of Psychology, Faculty of Health and Medical Sciences, University of Adelaide
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Lab Head, Gynaecological Cancer Research Group, Lowy Cancer Rearch Centre, UNSW Sydney
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Associate Professor and Program Authority, UNSW Sydney
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Consultant Senior Lecturer in Clinical Genetics, UCL
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Professor of Genetics, University of Newcastle
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Professor of Macromolecular Structure and Function, Imperial College London
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Group Leader, Signal Transduction Laboratory, Queensland Institute of Medical Research
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Emeritus Professor of Law, University of Tasmania
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Professor of molecular and medical genetics, Oregon Health & Science University
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PhD Candidate & Research Fellow, University of Tasmania
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Professor of Genetics and Director for Clinical Operations in the Center for Genomic Health, Yale University
