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A mural in Rome depicts a white dove parachuting vials of COVID-19 vaccine. Several COVID-19 vaccines are based on a viral vector developed by Canadian Frank Graham decades ago. (AP Photo/Gregorio Borgia)

How the puzzle of viral vector vaccines was solved, leading to today’s COVID-19 shots

Viral vectors are modified viruses that trigger an immune response without causing infection. The vector that’s used in several COVID-19 vaccines was created decades ago by Canadian Frank Graham.
A health-care worker prepares a dose of the Pfizer-BioNTech COVID-19 vaccine at a UHN COVID-19 vaccine clinic in Toronto on Thursday, January 7, 2021. THE CANADIAN PRESS/Nathan Denette

The roots of Canada’s COVID-19 vaccine shortage go back decades

Behind Canada’s current COVID-19 vaccine shortage is a decades-long tale of unheeded warnings, missed opportunities and dismantled resources that was never going to end well.

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