Functional precision medicine works to take the guesswork out of deciding which drug to try next for patients with cancers that don’t respond to standard treatments.
T cells recognize and kill cancer cells but quickly lose their effectiveness. This fast dysfunction may help explain why immunotherapy doesn’t lead to long-term remission for many patients.
Glioblastoma is the most aggressive type of brain cancer, causing significant decline in cognitive function. New research suggests a common anti-seizure drug could help control tumor growth.
Chengsheng Wu, University of California, San Diego; David Cheresh, University of California, San Diego, and Sara Weis, University of California, San Diego
Some cancers are notoriously resistant to chemotherapy and not curable with surgery. Stopping tumors from adapting to the harsh microenvironments of the body could be a potential treatment avenue.
Gregory Allen, University of California, San Francisco
Immunotherapy has the potential to eliminate tumors, but works best for select patients. Engineering T cells to bypass cancer’s defenses could help expand treatment eligibility to more patients.
One enzyme plays a key role in how tumor cells replicate and divide indefinitely. Identifying the genes that give these cells their immortality could provide new drug targets to treat cancer.
Multicancer early detection tests are among the priorities of the Biden administration’s Cancer Moonshot. The tests show promise, but questions remain about when and how to use them.
In a new study, a team of US scientists have used gene editing to change the genetic code of white blood cells and transform them into more efficient tumor fighting cells. How did they do it?
Researchers are trying to boost the power of our immune system by genetically altering our white blood cells and transforming them into super-soldiers to fight cancer.
Oxygen is vital for life, so much so that cells can sense when there isn’t enough and adapt almost instantly. So how do they do it? The winners of the 2019 Nobel Prize for Physiology figured it out.
Mariano Barbacid, Centro Nacional de Investigaciones Oncológicas CNIO
Pancreatic cancer currently has one of the least optimistic prognosis, with just 5% of patients surviving five years after diagnosis. A recent study opens a door to hope.
When you think of viruses, you might think of the horrible illnesses they cause, like flu or Ebola. But now researchers are learning how to use the unique traits of viruses to treat disease.
Sea turtles contend with a contagious disease that causes debilitating tumors. Genetic analysis is helping researchers figure out precision medicine-based treatments for the turtles.
Research has resulted in advances in treating breast cancer in recent decades, but a wide gap exists in mortality rates between African-American women and white women. Here’s a look into why.
Breast cancer awareness month may be over, but don’t put away your pink. The disease is with us year-round. While researchers have found several ways to treat it, here are some things to know.
A diagnosis of glioblastoma did not keep John McCain from the Capitol to cast a crucial vote that could end Obamacare. His actions are a reminder that stats are one thing but human beings, another.
Professor of Clinical and Diagnostic Sciences, Associate Dean of Research and Innovation in the School of Health Professions, University of Alabama at Birmingham