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Articles on Alzheimer's disease

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Alzheimer’s disease is characterized by progressive memory loss, spatial disorientation and many other cognitive and behavioural disorders that ultimately lead to a state of total dependence. (Shutterstock)

FDA approval of controversial Alzheimer’s drug could delay discovery of more promising treatments

The new drug is based on the idea that a build-up of amyloid in the brain leads to the disease. But that hypothesis has been under scrutiny lately.
Do the benefits of approving a drug before confirming it works outweigh the potential costs? monkeybusinessimages/iStock via Getty Images Plus

The FDA’s big gamble on the new Alzheimer’s drug

The FDA approved Alzheimer’s disease drug aducanumab despite minimal evidence of its efficacy. Whether this decision ultimately hurts or helps patients depends on data researchers don’t yet have.
Isolation and segregation create and reinforce another kind of barrier to those with dementia: stigma. (Shutterstock)

How communities can fight the stigma that isolates people with dementia

‘Dementia friendly’ communities seek to support people with memory loss, recognize them as equals, celebrate their contributions and enable them to live with purpose in welcoming communities.
The colors in this microscope photo of a fruit fly brain show different types of neurons and the cells that surround them in the brain. Sarah DeGenova Ackerman

Astrocyte cells in the fruit fly brain are an on-off switch that controls when neurons can change and grow

Adaptable neurons are tied to learning and memory but also to neurological disorders. By studying fruit flies, researchers found a mechanism that controls neuroplasticity.
Currently, the only approved drugs for Alzheimer’s merely alleviate some of the symptoms — partially and temporarily — but do not stop the disease from progressing. (Shutterstock)

Why don’t we have a cure for Alzheimer’s disease?

It was first officially described 115 years ago, but we still do not have a cure for Alzheimer’s disease. The human brain is extremely complex, and Alzheimer’s is its most complex disease.
A new study says African Americans with dementia carry a higher risk for COVID-19 than whites with dementia. kate_sept2004/Getty Images

Dementia patients are at greater risk for COVID-19, particularly African Americans and people with vascular dementia

Because dementia patients are more likely to acquire COVID-19, and because so many live in close-quarter facilities – like nursing homes – it’s critical to vaccinate them as quickly as possible.
Air pollution exposure during mid to early life may be more important to developing Alzheimer’s disease than doctors realized. Cecilie Arcurs via Getty Images

Air pollution may contribute to Alzheimer’s and dementia risk – here’s what we’re learning from brain scans

The tiny air pollutants known as PM2.5, emitted by vehicles, factories and power plants, aren’t just a hazard for lungs. A study finds more brain shrinkage in older women exposed to pollution.
More than half of patients with dementia also suffer from depression. If the depression remains untreated, the associated memory and cognitive problems worsen. Conversely, a significant history of depression seems to be a risk factor for dementia. (Pixabay)

Depression and dementia in the age of COVID-19: Two sides, one coin

Dementia and depression are two diagnoses that rob older adults of health and happiness. Despite their obvious differences, it is becoming ever more apparent that the two conditions are connected.

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