Action is needed to hold off a wave of dementia cases in an aging population. One of the most effective tools to reduce the prevalence of dementia is to address modifiable factors.
A new theory of Alzheimer’s disease reassesses the role of beta-amyloid in the brain.
(AP Photo/Evan Vucci)
Alzheimer’s may not be primarily a disease of the brain. It may be a disorder of the immune system within the brain. Beta-amyloid may not be an abnormal protein, but part of the brain’s immune system.
A thinning of the retina is associated with earlier ageing of the brain. Widely available retinal imaging could help detect cognitive decline in its earliest stages.
Rhesus macaques experience an aging process similar to people’s.
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Nonhuman primates like rhesus monkeys share certain characteristics with people that may make them better study subjects than mice for research on neurodegenerative diseases.
From thalidomide to resveratrol, molecules with the exact same chemical properties can have drastically different effects in the body depending on how they’re arranged in space.
Inflammatory cells surrounding amyloid plaque and activation of astrocytes, critical in maintaining the brain health.
Curtin Health Innovation Research Institute
Not all Alzheimer’s research has been compromised by allegations of scientific fraud. But we should interrogate whether the governing bodies of research and drug approvals are truly effective.
Communities that are underrepresented in research may also be at increased risk for dementia, or tend to experience dementia differently, often with poorer quality of care, later diagnoses and at possibly higher rates than the general population.
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Much dementia research does not reflect ethnically diverse communities. Studies used to make policy, clinical and investment decisions in dementia should reflect the diverse Canadian population.
Noradrenergic drugs were shown to improve some brain function and feelings of apathy.
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Because they help to create a shared understanding, metaphors can play a critical role in navigating the gap between the knowledge patients and health-care providers bring.
It hasn’t been known until now to what extent your night’s sleep affects short-term dementia symptoms.
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